HitPredict

Interactor 1: RASN (P01111)
GTPase NRas (EC 3.6.5.2) (Transforming protein N-Ras)
Gene: NRAS

Interactor 2: NECT1 (Q15223)
Nectin-1 (Herpes virus entry mediator C) (Herpesvirus entry mediator C) (HveC) (Herpesvirus Ig-like receptor) (HIgR) (Nectin cell adhesion molecule 1) (Poliovirus receptor-related protein 1) (CD antigen CD111)
Gene: NECTIN1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	30194290
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Ras~V-set
Common GO terms	GO:0005886 - plasma membrane GO:0016020 - membrane GO:0044877 - protein-containing complex binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 189 Hs			1 517
+	Hs
		350183 RASK_HUMAN (16-189): 7.56e-85: 249: 85.71		NECT1_HUMAN (1-517): 2.58e-113: 347: 100.00
+	Hs
		350416 RASK_HUMAN (16-189): 7.56e-85: 249: 85.71		NECT2_HUMAN (27-406): 1.14e-69: 234: 31.82
+	Hs
		1070332 RAB35_HUMAN (4-171): 6.96e-84: 247: 34.71		NECT2_HUMAN (27-406): 1.14e-69: 234: 31.82
+	Hs
		350513 RASK_HUMAN (16-189): 7.56e-85: 249: 85.71		CADM1_HUMAN (19-394): 1.45e-68: 228: 19.02
+	Hs
		348836 RASN_HUMAN (1-189): 9.9e-80: 236: 100.00		NECT2_HUMAN (27-406): 1.14e-69: 234: 31.82
+	Hs
		350584 RASK_HUMAN (16-189): 7.56e-85: 249: 85.71		NECT3_HUMAN (24-517): 1.69e-62: 215: 29.03
+	Hs
		781705 RAB35_HUMAN (4-171): 6.96e-84: 247: 34.71		OX2G_HUMAN (14-245): 1.69e-64: 212: 25.32
+	Hs
		348808 RASN_HUMAN (1-189): 9.9e-80: 236: 100.00		CADM4_HUMAN (34-404): 1.98e-55: 192: 19.58
+	Hs
		350424 RASK_HUMAN (16-189): 7.56e-85: 249: 85.71		NEO1_HUMAN (28-498): 1.77e-43: 167: 14.49
+	Hs
		348841 RASN_HUMAN (1-189): 9.9e-80: 236: 100.00		NEO1_HUMAN (28-498): 1.77e-43: 167: 14.49
+	Hs
		350455 RASK_HUMAN (16-189): 7.56e-85: 249: 85.71		KIRR1_HUMAN (29-489): 3.31e-35: 141: 13.74
+	Hs
		1070344 RAB35_HUMAN (4-171): 6.96e-84: 247: 34.71		KIRR1_HUMAN (29-489): 3.31e-35: 141: 13.74
+	Hs
		348867 RASN_HUMAN (1-189): 9.9e-80: 236: 100.00		KIRR1_HUMAN (29-489): 3.31e-35: 141: 13.74
+	Hs
		350746 RASK_HUMAN (16-189): 7.56e-85: 249: 85.71		ROBO1_HUMAN (20-508): 1.25e-29: 125: 10.69
+	Hs
		1070491 RAB35_HUMAN (4-171): 6.96e-84: 247: 34.71		ROBO1_HUMAN (20-508): 1.25e-29: 125: 10.69
+	Hs
		350572 RASK_HUMAN (16-189): 7.56e-85: 249: 85.71		ROBO2_HUMAN (235-517): 7.1e-25: 111: 12.95
+	Hs
		349841 RASK_HUMAN (16-189): 7.56e-85: 249: 85.71		NCAM1_HUMAN (28-360): 1.99e-20: 97.1: 13.41
+	Hs
		530172 RAB35_HUMAN (4-171): 6.96e-84: 247: 34.71		NCAM1_HUMAN (28-360): 1.99e-20: 97.1: 13.41
+	Hs
		348489 RASN_HUMAN (1-189): 9.9e-80: 236: 100.00		NCAM1_HUMAN (28-360): 1.99e-20: 97.1: 13.41
+	Hs
		350405 RASK_HUMAN (16-189): 7.56e-85: 249: 85.71		TITIN_HUMAN (154-516): 9.68e-09: 60.5: 8.27