HitPredict

Interactor 1: RASN (P01111)
GTPase NRas (EC 3.6.5.2) (Transforming protein N-Ras)
Gene: NRAS

Interactor 2: S4A8 (Q2Y0W8)
Electroneutral sodium bicarbonate exchanger 1 (Electroneutral Na(+)-driven Cl-HCO3 exchanger) (Solute carrier family 4 member 8) (k-NBC3)
Gene: SLC4A8

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	28514442
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0016020 - membrane
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 189 Hs			1 1093
+	Hs
		350209 RASK_HUMAN (16-189): 7.56e-85: 249: 85.71		S4A8_HUMAN (1-1093): 0: 1601: 100.00
+	Hs
		350749 RASK_HUMAN (16-189): 7.56e-85: 249: 85.71		S4A4_HUMAN (19-1009): 0: 1229: 52.89
+	Hs
		349794 RASK_HUMAN (16-189): 7.56e-85: 249: 85.71		B3A2_HUMAN (59-1035): 0: 1074: 39.05
+	Hs
		392680 RAB35_HUMAN (4-171): 6.96e-84: 247: 34.71		B3A2_HUMAN (59-1035): 0: 1074: 39.05
+	Hs
		348466 RASN_HUMAN (1-189): 9.9e-80: 236: 100.00		B3A2_HUMAN (59-1035): 0: 1074: 39.05
+	Hs
		392668 RAB2A_HUMAN (4-185): 1.53e-73: 222: 31.52		B3A2_HUMAN (59-1035): 0: 1074: 39.05
+	Hs
		350745 RASK_HUMAN (16-189): 7.56e-85: 249: 85.71		S4A7_HUMAN (17-275): 1.08e-98: 341: 59.23
+	Hs
		1070490 RAB35_HUMAN (4-171): 6.96e-84: 247: 34.71		S4A7_HUMAN (17-275): 1.08e-98: 341: 59.23
+	Hs
		349042 RASN_HUMAN (1-189): 9.9e-80: 236: 100.00		S4A7_HUMAN (17-275): 1.08e-98: 341: 59.23
+	Hs
		349774 RASH_HUMAN (1-188): 8.6e-78: 232: 85.64		S4A7_HUMAN (17-275): 1.08e-98: 341: 59.23
+	Hs
		914505 RB11A_HUMAN (4-184): 1.5e-74: 224: 33.88		S4A7_HUMAN (17-275): 1.08e-98: 341: 59.23
+	Hs
		895342 RAB2A_HUMAN (4-185): 1.53e-73: 222: 31.52		S4A7_HUMAN (17-275): 1.08e-98: 341: 59.23