HitPredict

Interactor 1: RASN (P01111)
GTPase NRas (EC 3.6.5.2) (Transforming protein N-Ras)
Gene: NRAS

Interactor 2: DOCK8 (Q8NF50)
Dedicator of cytokinesis protein 8
Gene: DOCK8

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	30442766
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	DHR-2_Lobe_B~Ras, DHR-2_Lobe_C~Ras
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0016020 - membrane
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 189 Hs			1 2099
+	Hs
		350368 RASK_HUMAN (16-189): 7.56e-85: 249: 85.71		DOCK8_HUMAN (1-2099): 0: 2775: 100.00
+	Hs
		349503 RASH_HUMAN (1-188): 8.6e-78: 232: 85.64		DOCK8_HUMAN (1-2099): 0: 2775: 100.00
+	Hs
		350459 RASK_HUMAN (16-189): 7.56e-85: 249: 85.71		DOCK7_HUMAN (7-2092): 0: 2471: 55.37
+	Hs
		1070346 RAB35_HUMAN (4-171): 6.96e-84: 247: 34.71		DOCK7_HUMAN (7-2092): 0: 2471: 55.37
+	Hs
		348871 RASN_HUMAN (1-189): 9.9e-80: 236: 100.00		DOCK7_HUMAN (7-2092): 0: 2471: 55.37
+	Hs
		895227 RAB2A_HUMAN (4-185): 1.53e-73: 222: 31.52		DOCK6_HUMAN (4-2092): 0: 2401: 51.16
+	Hs
		350225 RASK_HUMAN (16-189): 7.56e-85: 249: 85.71		DOC11_HUMAN (22-177): 2.25e-43: 176: 22.50
+	Hs
		350515 RASK_HUMAN (16-189): 7.56e-85: 249: 85.71		DOCK9_HUMAN (5-177): 2.21e-40: 167: 19.89
+	Hs
		1070378 RAB35_HUMAN (4-171): 6.96e-84: 247: 34.71		DOCK9_HUMAN (5-177): 2.21e-40: 167: 19.89
+	Hs
		349619 RASH_HUMAN (1-188): 8.6e-78: 232: 85.64		DOCK9_HUMAN (5-177): 2.21e-40: 167: 19.89
+	Hs
		350167 RASK_HUMAN (16-189): 7.56e-85: 249: 85.71		DOCK1_HUMAN (560-867): 5.67e-28: 126: 19.33
+	Hs
		350557 RASK_HUMAN (16-189): 7.56e-85: 249: 85.71		DOCK5_HUMAN (560-867): 2.82e-24: 114: 17.49
+	Hs
		349648 RASH_HUMAN (1-188): 8.6e-78: 232: 85.64		DOCK5_HUMAN (560-867): 2.82e-24: 114: 17.49