HitPredict

Interactor 1: RASN (P01111)
GTPase NRas (EC 3.6.5.2) (Transforming protein N-Ras)
Gene: NRAS

Interactor 2: PKP4 (Q99569)
Plakophilin-4 (p0071)
Gene: PKP4

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	1.00	0.754

Property	Details
Experiments	30639242, 30194290
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Arm~Ras
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 189 Hs			1 1192
+	Hs
		350478 RASK_HUMAN (16-189): 7.56e-85: 249: 85.71		PKP4_HUMAN (1-1192): 0: 1148: 100.00
+	Hs
		1070361 RAB35_HUMAN (4-171): 6.96e-84: 247: 34.71		PKP4_HUMAN (1-1192): 0: 1148: 100.00
+	Hs
		350487 RASK_HUMAN (16-189): 7.56e-85: 249: 85.71		PKP2_HUMAN (156-1014): 1.57e-160: 502: 24.78
+	Hs
		1070365 RAB35_HUMAN (4-171): 6.96e-84: 247: 34.71		PKP2_HUMAN (156-1014): 1.57e-160: 502: 24.78
+	Hs
		350719 RASK_HUMAN (16-189): 7.56e-85: 249: 85.71		PKP3_HUMAN (218-1014): 2.04e-152: 478: 26.92
+	Hs
		717259 RAB8B_HUMAN (4-181): 2.25e-85: 251: 36.11		CTNB1_HUMAN (311-1123): 4.61e-149: 469: 16.00
+	Hs
		349923 RASK_HUMAN (16-189): 7.56e-85: 249: 85.71		CTNB1_HUMAN (311-1123): 4.61e-149: 469: 16.00
+	Hs
		717100 RAB35_HUMAN (4-171): 6.96e-84: 247: 34.71		CTNB1_HUMAN (311-1123): 4.61e-149: 469: 16.00
+	Hs
		349025 RASN_HUMAN (1-189): 9.9e-80: 236: 100.00		PKP3_HUMAN (218-1014): 2.04e-152: 478: 26.92
+	Hs
		348538 RASN_HUMAN (1-189): 9.9e-80: 236: 100.00		CTNB1_HUMAN (311-1123): 4.61e-149: 469: 16.00
+	Hs
		350173 RASK_HUMAN (16-189): 7.56e-85: 249: 85.71		TRIPC_HUMAN (110-1126): 7.22e-126: 429: 11.99
+	Hs
		542399 RAB8B_HUMAN (4-181): 2.25e-85: 251: 36.11		PLAK_HUMAN (316-1101): 3.54e-125: 404: 16.54
+	Hs
		349846 RASK_HUMAN (16-189): 7.56e-85: 249: 85.71		PLAK_HUMAN (316-1101): 3.54e-125: 404: 16.54
+	Hs
		542331 RAB35_HUMAN (4-171): 6.96e-84: 247: 34.71		PLAK_HUMAN (316-1101): 3.54e-125: 404: 16.54
+	Hs
		239017 RASK_HUMAN (16-189): 7.56e-85: 249: 85.71		CTND1_HUMAN (26-872): 2.01e-72: 263: 13.69
+	Hs
		349994 RASK_HUMAN (16-189): 7.56e-85: 249: 85.71		GDS1_HUMAN (530-972): 4.81e-75: 263: 16.70
+	Hs
		239136 RAB35_HUMAN (4-171): 6.96e-84: 247: 34.71		CTND1_HUMAN (26-872): 2.01e-72: 263: 13.69
+	Hs
		239015 RASN_HUMAN (1-189): 9.9e-80: 236: 100.00		CTND1_HUMAN (26-872): 2.01e-72: 263: 13.69
+	Hs
		348587 RASN_HUMAN (1-189): 9.9e-80: 236: 100.00		GDS1_HUMAN (530-972): 4.81e-75: 263: 16.70
+	Hs
		119749 RASK_HUMAN (16-189): 7.56e-85: 249: 85.71		ARVC_HUMAN (33-851): 3.37e-51: 198: 13.83