HitPredict

Interactor 1: RASN (P01111)
GTPase NRas (EC 3.6.5.2) (Transforming protein N-Ras)
Gene: NRAS

Interactor 2: NEB1 (Q9ULJ8)
Neurabin-1 (Neurabin-I) (Neural tissue-specific F-actin-binding protein I) (Protein phosphatase 1 regulatory subunit 9A)
Gene: PPP1R9A

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.553

Property	Details
Experiments	30639242
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PDZ~Ras
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 189 Hs			1 1098
+	Hs
		350676 RASK_HUMAN (16-189): 7.56e-85: 249: 85.71		NEB1_HUMAN (1-1098): 6.8e-118: 392: 100.00
+	Hs
		1070451 RAB35_HUMAN (4-171): 6.96e-84: 247: 34.71		NEB1_HUMAN (1-1098): 6.8e-118: 392: 100.00
+	Hs
		350420 RASK_HUMAN (16-189): 7.56e-85: 249: 85.71		DLG3_HUMAN (311-1098): 1.22e-71: 257: 13.03
+	Hs
		350124 RASK_HUMAN (16-189): 7.56e-85: 249: 85.71		DLG1_HUMAN (225-1097): 2.22e-67: 246: 13.80
+	Hs
		1021495 RAB35_HUMAN (4-171): 6.96e-84: 247: 34.71		DLG1_HUMAN (225-1097): 2.22e-67: 246: 13.80
+	Hs
		349543 RASH_HUMAN (1-188): 8.6e-78: 232: 85.64		DLG3_HUMAN (311-1098): 1.22e-71: 257: 13.03
+	Hs
		348639 RASN_HUMAN (1-189): 9.9e-80: 236: 100.00		DLG1_HUMAN (225-1097): 2.22e-67: 246: 13.80
+	Hs
		349277 RASH_HUMAN (1-188): 8.6e-78: 232: 85.64		DLG1_HUMAN (225-1097): 2.22e-67: 246: 13.80
+	Hs
		914039 RB11A_HUMAN (4-184): 1.5e-74: 224: 33.88		DLG1_HUMAN (225-1097): 2.22e-67: 246: 13.80
+	Dm
		442999 RAS1_DROME (1-170): 2.87e-90: 263: 83.53		Q8IPP3_DROME (487-680): 5.2e-32: 138: 28.37
+	Dm
		442992 RAS1_DROME (1-170): 2.87e-90: 263: 83.53		Q24279_DROME (487-650): 6.61e-32: 137: 29.27
+	Dm
		443003 RAS1_DROME (1-170): 2.87e-90: 263: 83.53		Q95TT5_DROME (487-628): 7.72e-32: 137: 31.69
+	Mm
		918987 RAB1A_MOUSE (4-187): 1.35e-76: 229: 33.33		NEB2_MOUSE (1-826): 5.97e-43: 171: 43.42
+	Hs
		350005 RASK_HUMAN (16-189): 7.56e-85: 249: 85.71		AFAD_HUMAN (419-593): 1.96e-23: 110: 30.11
+	Hs
		348594 RASN_HUMAN (1-189): 9.9e-80: 236: 100.00		AFAD_HUMAN (419-593): 1.96e-23: 110: 30.11
+	Hs
		350121 RASK_HUMAN (16-189): 7.56e-85: 249: 85.71		PTN13_HUMAN (2-937): 2.68e-18: 93.5: 11.65
+	Hs
		349224 RASH_HUMAN (1-188): 8.6e-78: 232: 85.64		AFAD_HUMAN (419-593): 1.96e-23: 110: 30.11
+	Hs
		1020162 RAB35_HUMAN (4-171): 6.96e-84: 247: 34.71		PTN13_HUMAN (2-937): 2.68e-18: 93.5: 11.65
+	Hs
		350374 RASK_HUMAN (16-189): 7.56e-85: 249: 85.71		INADL_HUMAN (300-819): 1.83e-15: 84: 10.38
+	Hs
		349510 RASH_HUMAN (1-188): 8.6e-78: 232: 85.64		INADL_HUMAN (300-819): 1.83e-15: 84: 10.38