HitPredict

Interactor 1: RASN (P01111)
GTPase NRas (EC 3.6.5.2) (Transforming protein N-Ras)
Gene: NRAS

Interactor 2: NUMBL (Q9Y6R0)
Numb-like protein (Numb-related protein) (Numb-R)
Gene: NUMBL

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.50	0.533

Property	Details
Experiments	30442766, 30639242
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 189 Hs			1 609
+	Hs
		350748 RASK_HUMAN (16-189): 7.56e-85: 249: 85.71		NUMBL_HUMAN (1-609): 3.31e-87: 285: 100.00
+	Hs
		1070492 RAB35_HUMAN (4-171): 6.96e-84: 247: 34.71		NUMBL_HUMAN (1-609): 3.31e-87: 285: 100.00
+	Hs
		349776 RASH_HUMAN (1-188): 8.6e-78: 232: 85.64		NUMBL_HUMAN (1-609): 3.31e-87: 285: 100.00
+	Hs
		914507 RB11A_HUMAN (4-184): 1.5e-74: 224: 33.88		NUMBL_HUMAN (1-609): 3.31e-87: 285: 100.00
+	Hs
		349976 RASK_HUMAN (16-189): 7.56e-85: 249: 85.71		NUMB_HUMAN (42-609): 2.54e-68: 235: 46.87
+	Hs
		833596 RAB35_HUMAN (4-171): 6.96e-84: 247: 34.71		NUMB_HUMAN (42-609): 2.54e-68: 235: 46.87
+	Hs
		348573 RASN_HUMAN (1-189): 9.9e-80: 236: 100.00		NUMB_HUMAN (42-609): 2.54e-68: 235: 46.87
+	Hs
		349190 RASH_HUMAN (1-188): 8.6e-78: 232: 85.64		NUMB_HUMAN (42-609): 2.54e-68: 235: 46.87
+	Hs
		350414 RASK_HUMAN (16-189): 7.56e-85: 249: 85.71		ANS1A_HUMAN (7-259): 2.46e-57: 210: 20.23
+	Hs
		833569 RB11A_HUMAN (4-184): 1.5e-74: 224: 33.88		NUMB_HUMAN (42-609): 2.54e-68: 235: 46.87
+	Hs
		833561 RAB2A_HUMAN (4-185): 1.53e-73: 222: 31.52		NUMB_HUMAN (42-609): 2.54e-68: 235: 46.87
+	Mm
		1206680 RAB1B_MOUSE (4-187): 2e-75: 226: 32.47		ANS1B_MOUSE (7-256): 3.08e-59: 216: 21.32
+	Hs
		253519 RASK_HUMAN (16-189): 7.56e-85: 249: 85.71		CAPON_HUMAN (68-316): 6.44e-39: 151: 19.05
+	Hs
		253561 RAB35_HUMAN (4-171): 6.96e-84: 247: 34.71		CAPON_HUMAN (68-316): 6.44e-39: 151: 19.05
+	Hs
		297806 RASK_HUMAN (16-189): 7.56e-85: 249: 85.71		K0754_HUMAN (173-497): 2.24e-24: 111: 11.25
+	Hs
		297829 RAB35_HUMAN (4-171): 6.96e-84: 247: 34.71		K0754_HUMAN (173-497): 2.24e-24: 111: 11.25
+	Hs
		297805 RASN_HUMAN (1-189): 9.9e-80: 236: 100.00		K0754_HUMAN (173-497): 2.24e-24: 111: 11.25
+	Hs
		253530 RALA_HUMAN (4-169): 7.15e-59: 184: 53.89		CAPON_HUMAN (68-316): 6.44e-39: 151: 19.05
+	Hs
		203195 RASK_HUMAN (16-189): 7.56e-85: 249: 85.71		SYNJ1_HUMAN (217-607): 6.26e-12: 70.9: 11.21