HitPredict

Interactor 1: RASH (P01112)
GTPase HRas (EC 3.6.5.2) (H-Ras-1) (Ha-Ras) (Transforming protein p21) (c-H-ras) (p21ras) [Cleaved into: GTPase HRas, N-terminally processed]
Gene: HRAS

Interactor 2: AT2B4 (P23634)
Plasma membrane calcium-transporting ATPase 4 (PMCA4) (EC 7.2.2.10) (Matrix-remodeling-associated protein 1) (Plasma membrane calcium ATPase isoform 4) (Plasma membrane calcium pump isoform 4)
Gene: ATP2B4

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.60	0.640

Property	Details
Experiments	30442766, 30639242, 30194290
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0006357 - regulation of transcription by RNA polymerase II GO:0010629 - negative regulation of gene expression GO:0098978 - glutamatergic synapse
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 189 Hs			1 1241
+	Hs
		348515 RASN_HUMAN (1-188): 6.47e-88: 257: 85.64		AT2B4_HUMAN (1-1241): 0: 1300: 100.00
+	Hs
		349882 RASK_HUMAN (1-188): 2.04e-84: 248: 86.24		AT2B4_HUMAN (1-1241): 0: 1300: 100.00
+	Hs
		348504 RASN_HUMAN (1-188): 6.47e-88: 257: 85.64		AT2B1_HUMAN (1-1241): 0: 1148: 72.46
+	Hs
		349870 RASK_HUMAN (1-188): 2.04e-84: 248: 86.24		AT2B1_HUMAN (1-1241): 0: 1148: 72.46
+	Hs
		588580 RB11A_HUMAN (4-178): 4.48e-74: 223: 33.90		AT2B1_HUMAN (1-1241): 0: 1148: 72.46
+	Hs
		349116 RASH_HUMAN (16-189): 5.68e-73: 219: 100.00		AT2B1_HUMAN (1-1241): 0: 1148: 72.46
+	Hs
		348468 RASN_HUMAN (1-188): 6.47e-88: 257: 85.64		AT1A1_HUMAN (34-1053): 0: 737: 23.37
+	Hs
		349796 RASK_HUMAN (1-188): 2.04e-84: 248: 86.24		AT1A1_HUMAN (34-1053): 0: 737: 23.37
+	Hs
		393146 RB11A_HUMAN (4-178): 4.48e-74: 223: 33.90		AT1A1_HUMAN (34-1053): 0: 737: 23.37
+	Hs
		349060 RASH_HUMAN (16-189): 5.68e-73: 219: 100.00		AT1A1_HUMAN (34-1053): 0: 737: 23.37