HitPredict

Interactor 1: RASH (P01112)
GTPase HRas (EC 3.6.5.2) (H-Ras-1) (Ha-Ras) (Transforming protein p21) (c-H-ras) (p21ras) [Cleaved into: GTPase HRas, N-terminally processed]
Gene: HRAS

Interactor 2: SH3K1 (Q96B97)
SH3 domain-containing kinase-binding protein 1 (CD2-binding protein 3) (CD2BP3) (Cbl-interacting protein of 85 kDa) (Human Src family kinase-binding protein 1) (HSB-1)
Gene: SH3KBP1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	18048363
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0006897 - endocytosis
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 189 Hs			1 665
+	Hs
		914272 RB11A_HUMAN (4-178): 4.48e-74: 223: 33.90		SH3K1_HUMAN (1-665): 8.63e-127: 391: 100.00
+	Hs
		348603 RASN_HUMAN (1-188): 6.47e-88: 257: 85.64		GRB2_HUMAN (2-158): 6.97e-33: 128: 19.91
+	Hs
		350048 RASK_HUMAN (1-188): 2.04e-84: 248: 86.24		GRB2_HUMAN (2-158): 6.97e-33: 128: 19.91
+	Hs
		557649 RB11A_HUMAN (4-178): 4.48e-74: 223: 33.90		NCK1_HUMAN (104-421): 1.23e-32: 131: 16.81
+	Hs
		913994 RB11A_HUMAN (4-178): 4.48e-74: 223: 33.90		GRB2_HUMAN (2-158): 6.97e-33: 128: 19.91
+	Hs
		924750 RAB8B_HUMAN (4-180): 8.57e-74: 222: 36.31		GRB2_HUMAN (2-158): 6.97e-33: 128: 19.91
+	Hs
		350195 RASK_HUMAN (1-188): 2.04e-84: 248: 86.24		ITSN1_HUMAN (68-454): 2.48e-21: 101: 14.01
+	Hs
		349233 RASH_HUMAN (16-189): 5.68e-73: 219: 100.00		GRB2_HUMAN (2-158): 6.97e-33: 128: 19.91
+	Hs
		924599 RB11B_HUMAN (4-171): 1.34e-72: 219: 34.12		GRB2_HUMAN (2-158): 6.97e-33: 128: 19.91
+	Hs
		924749 RAB1C_HUMAN (4-186): 3.44e-72: 218: 32.47		GRB2_HUMAN (2-158): 6.97e-33: 128: 19.91
+	Hs
		235463 RASK_HUMAN (1-188): 2.04e-84: 248: 86.24		VINEX_HUMAN (67-445): 2.37e-15: 81.7: 19.82
+	Hs
		914091 RB11A_HUMAN (4-178): 4.48e-74: 223: 33.90		ITSN1_HUMAN (68-454): 2.48e-21: 101: 14.01
+	Hs
		349341 RASH_HUMAN (16-189): 5.68e-73: 219: 100.00		ITSN1_HUMAN (68-454): 2.48e-21: 101: 14.01
+	Hs
		924763 RIT1_HUMAN (3-167): 1.65e-56: 179: 51.81		GRB2_HUMAN (2-158): 6.97e-33: 128: 19.91
+	Hs
		349105 RASH_HUMAN (16-189): 5.68e-73: 219: 100.00		VAV_HUMAN (84-158): 4.66e-13: 74.7: 28.95