HitPredict

Interactor 1: RASH (P01112)
GTPase HRas (EC 3.6.5.2) (H-Ras-1) (Ha-Ras) (Transforming protein p21) (c-H-ras) (p21ras) [Cleaved into: GTPase HRas, N-terminally processed]
Gene: HRAS

Interactor 2: PACN3 (Q9UKS6)
Protein kinase C and casein kinase substrate in neurons protein 3 (SH3 domain-containing protein 6511)
Gene: PACSIN3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	30639242
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0006897 - endocytosis
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 189 Hs			1 424
+	Hs
		349006 RASN_HUMAN (1-188): 6.47e-88: 257: 85.64		PACN2_HUMAN (4-422): 2.86e-77: 249: 48.96
+	Hs
		350683 RASK_HUMAN (1-188): 2.04e-84: 248: 86.24		PACN2_HUMAN (4-422): 2.86e-77: 249: 48.96
+	Hs
		914458 RB11A_HUMAN (4-178): 4.48e-74: 223: 33.90		PACN2_HUMAN (4-422): 2.86e-77: 249: 48.96
+	Hs
		350116 RASK_HUMAN (1-188): 2.04e-84: 248: 86.24		FCHO2_HUMAN (7-369): 5.76e-41: 157: 15.03
+	Hs
		350125 RASK_HUMAN (1-188): 2.04e-84: 248: 86.24		MYO1E_HUMAN (2-422): 5.28e-39: 151: 14.03
+	Hs
		348989 RASN_HUMAN (1-188): 6.47e-88: 257: 85.64		BI2L1_HUMAN (50-422): 1.77e-34: 136: 13.60
+	Hs
		350656 RASK_HUMAN (1-188): 2.04e-84: 248: 86.24		BI2L1_HUMAN (50-422): 1.77e-34: 136: 13.60
+	Hs
		349271 RASH_HUMAN (16-189): 5.68e-73: 219: 100.00		FCHO2_HUMAN (7-369): 5.76e-41: 157: 15.03
+	Hs
		349278 RASH_HUMAN (16-189): 5.68e-73: 219: 100.00		MYO1E_HUMAN (2-422): 5.28e-39: 151: 14.03
+	Hs
		914434 RB11A_HUMAN (4-178): 4.48e-74: 223: 33.90		BI2L1_HUMAN (50-422): 1.77e-34: 136: 13.60
+	Hs
		349709 RASH_HUMAN (16-189): 5.68e-73: 219: 100.00		BI2L1_HUMAN (50-422): 1.77e-34: 136: 13.60
+	Hs
		350195 RASK_HUMAN (1-188): 2.04e-84: 248: 86.24		ITSN1_HUMAN (30-424): 3.23e-15: 80.2: 10.78
+	Hs
		350469 RASK_HUMAN (1-188): 2.04e-84: 248: 86.24		FNBP1_HUMAN (214-421): 7.83e-12: 69: 13.46
+	Hs
		914091 RB11A_HUMAN (4-178): 4.48e-74: 223: 33.90		ITSN1_HUMAN (30-424): 3.23e-15: 80.2: 10.78
+	Hs
		349341 RASH_HUMAN (16-189): 5.68e-73: 219: 100.00		ITSN1_HUMAN (30-424): 3.23e-15: 80.2: 10.78
+	Hs
		914298 RB11A_HUMAN (4-178): 4.48e-74: 223: 33.90		FNBP1_HUMAN (214-421): 7.83e-12: 69: 13.46