HitPredict

Interactor 1: RASH (P01112)
GTPase HRas (EC 3.6.5.2) (H-Ras-1) (Ha-Ras) (Transforming protein p21) (c-H-ras) (p21ras) [Cleaved into: GTPase HRas, N-terminally processed]
Gene: HRAS

Interactor 2: XCT (Q9UPY5)
Cystine/glutamate transporter (Amino acid transport system xc-) (Calcium channel blocker resistance protein CCBR1) (Solute carrier family 7 member 11) (xCT)
Gene: SLC7A11

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	30639242, 30194290
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0042127 - regulation of cell population proliferation
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 189 Hs			1 501
+	Hs
		349011 RASN_HUMAN (1-188): 6.47e-88: 257: 85.64		XCT_HUMAN (1-501): 1.35e-118: 359: 100.00
+	Hs
		350407 RASK_HUMAN (1-188): 2.04e-84: 248: 86.24		YLAT2_HUMAN (3-501): 5.33e-122: 368: 43.71
+	Hs
		350692 RASK_HUMAN (1-188): 2.04e-84: 248: 86.24		XCT_HUMAN (1-501): 1.35e-118: 359: 100.00
+	Hs
		348622 RASN_HUMAN (1-188): 6.47e-88: 257: 85.64		LAT1_HUMAN (23-498): 1.09e-104: 323: 47.28
+	Hs
		350085 RASK_HUMAN (1-188): 2.04e-84: 248: 86.24		LAT1_HUMAN (23-498): 1.09e-104: 323: 47.28
+	Hs
		914015 RB11A_HUMAN (4-178): 4.48e-74: 223: 33.90		LAT1_HUMAN (23-498): 1.09e-104: 323: 47.28
+	Hs
		349255 RASH_HUMAN (16-189): 5.68e-73: 219: 100.00		LAT1_HUMAN (23-498): 1.09e-104: 323: 47.28
+	Hs
		348593 RASN_HUMAN (1-188): 6.47e-88: 257: 85.64		S12A2_HUMAN (12-485): 3.69e-84: 284: 14.15
+	Hs
		350004 RASK_HUMAN (1-188): 2.04e-84: 248: 86.24		S12A2_HUMAN (12-485): 3.69e-84: 284: 14.15
+	Hs
		348588 RASN_HUMAN (1-188): 6.47e-88: 257: 85.64		CTR2_HUMAN (36-414): 4.19e-80: 264: 19.86
+	Hs
		348533 RASN_HUMAN (1-188): 6.47e-88: 257: 85.64		CTR1_HUMAN (34-414): 2.9e-79: 261: 20.24
+	Hs
		349996 RASK_HUMAN (1-188): 2.04e-84: 248: 86.24		CTR2_HUMAN (36-414): 4.19e-80: 264: 19.86
+	Hs
		349913 RASK_HUMAN (1-188): 2.04e-84: 248: 86.24		CTR1_HUMAN (34-414): 2.9e-79: 261: 20.24
+	Hs
		873901 RB11A_HUMAN (4-178): 4.48e-74: 223: 33.90		S12A2_HUMAN (12-485): 3.69e-84: 284: 14.15
+	Hs
		349223 RASH_HUMAN (16-189): 5.68e-73: 219: 100.00		S12A2_HUMAN (12-485): 3.69e-84: 284: 14.15
+	Hs
		854872 RB11A_HUMAN (4-178): 4.48e-74: 223: 33.90		CTR2_HUMAN (36-414): 4.19e-80: 264: 19.86
+	Hs
		349149 RASH_HUMAN (16-189): 5.68e-73: 219: 100.00		CTR1_HUMAN (34-414): 2.9e-79: 261: 20.24