HitPredict

Interactor 1: RASK (P01116)
GTPase KRas (EC 3.6.5.2) (K-Ras 2) (Ki-Ras) (c-K-ras) (c-Ki-ras) [Cleaved into: GTPase KRas, N-terminally processed]
Gene: KRAS

Interactor 2: PTPRM (P28827)
Receptor-type tyrosine-protein phosphatase mu (Protein-tyrosine phosphatase mu) (R-PTP-mu) (EC 3.1.3.48)
Gene: PTPRM

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	30639242
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Ras~fn3
Common GO terms	GO:0005737 - cytoplasm GO:0005886 - plasma membrane
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 189 Hs			1 1452
+	Hs
		349143 RASH_HUMAN (1-188): 6.53e-87: 255: 86.77		PTPRM_HUMAN (1-1452): 0: 1241: 100.00
+	Hs
		349111 RASH_HUMAN (1-188): 6.53e-87: 255: 86.77		PTPRA_HUMAN (691-1451): 0: 761: 32.00
+	Hs
		349275 RASH_HUMAN (1-188): 6.53e-87: 255: 86.77		PTPRJ_HUMAN (208-1451): 1.19e-115: 397: 14.94
+	Hs
		350120 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		PTPRJ_HUMAN (208-1451): 1.19e-115: 397: 14.94
+	Hs
		914038 RB11A_HUMAN (4-184): 2.43e-72: 219: 33.88		PTPRJ_HUMAN (208-1451): 1.19e-115: 397: 14.94
+	Hs
		349083 RASH_HUMAN (1-188): 6.53e-87: 255: 86.77		PTPRF_HUMAN (88-952): 6.12e-80: 294: 13.52
+	Hs
		489965 RAB35_HUMAN (4-187): 1.09e-82: 244: 31.28		PTPRF_HUMAN (88-952): 6.12e-80: 294: 13.52
+	Hs
		349822 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		PTPRF_HUMAN (88-952): 6.12e-80: 294: 13.52
+	Hs
		489934 RAB2A_HUMAN (4-183): 1.46e-75: 227: 32.97		PTPRF_HUMAN (88-952): 6.12e-80: 294: 13.52
+	Hs
		1031987 RAB35_HUMAN (4-187): 1.09e-82: 244: 31.28		PTPRS_HUMAN (30-951): 5.2e-62: 236: 12.49
+	Hs
		348514 RASN_HUMAN (1-189): 2.37e-85: 251: 85.19		PTPRG_HUMAN (915-1160): 7.11e-48: 190: 29.69
+	Hs
		617112 RAB35_HUMAN (4-187): 1.09e-82: 244: 31.28		PTPRG_HUMAN (915-1160): 7.11e-48: 190: 29.69
+	Hs
		349881 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		PTPRG_HUMAN (915-1160): 7.11e-48: 190: 29.69
+	Hs
		617093 RAB2A_HUMAN (4-183): 1.46e-75: 227: 32.97		PTPRG_HUMAN (915-1160): 7.11e-48: 190: 29.69
+	Hs
		616911 RAB13_HUMAN (4-186): 7.7e-72: 217: 36.76		PTPRB_HUMAN (358-973): 2.61e-11: 70.8: 11.66