HitPredict

Interactor 1: RASK (P01116)
GTPase KRas (EC 3.6.5.2) (K-Ras 2) (Ki-Ras) (c-K-ras) (c-Ki-ras) [Cleaved into: GTPase KRas, N-terminally processed]
Gene: KRAS

Interactor 2: ARF1 (P84077)
ADP-ribosylation factor 1 (EC 3.6.5.2)
Gene: ARF1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.60	0.640

Property	Details
Experiments	27684187, 30194290, 34079125
Identification Methods	affinity chromatography technology, proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000139 - Golgi membrane GO:0003924 - GTPase activity GO:0005525 - GTP binding GO:0005829 - cytosol GO:0005886 - plasma membrane and 1 others more... GO:0005925 - focal adhesion
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 189 Hs			1 181
+	Hs
		348599 RASN_HUMAN (1-189): 2.37e-85: 251: 85.19		ARF6_HUMAN (5-179): 2.19e-73: 219: 68.00
+	Hs
		912914 RAB35_HUMAN (4-187): 1.09e-82: 244: 31.28		ARF6_HUMAN (5-179): 2.19e-73: 219: 68.00
+	Hs
		348501 RASN_HUMAN (1-189): 2.37e-85: 251: 85.19		ARF4_HUMAN (1-180): 1.54e-69: 210: 80.56
+	Hs
		349231 RASH_HUMAN (1-188): 6.53e-87: 255: 86.77		RAB1A_HUMAN (3-180): 1.3e-66: 204: 18.58
+	Hs
		348612 RASN_HUMAN (1-189): 2.37e-85: 251: 85.19		ARF1_HUMAN (1-181): 5.85e-68: 206: 100.00
+	Hs
		348601 RASN_HUMAN (1-189): 2.37e-85: 251: 85.19		RAB1A_HUMAN (3-180): 1.3e-66: 204: 18.58
+	Hs
		574682 RAB35_HUMAN (4-187): 1.09e-82: 244: 31.28		ARF4_HUMAN (1-180): 1.54e-69: 210: 80.56
+	Hs
		950495 RAB35_HUMAN (4-187): 1.09e-82: 244: 31.28		ARF1_HUMAN (1-181): 5.85e-68: 206: 100.00
+	Hs
		350032 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		ARF6_HUMAN (5-179): 2.19e-73: 219: 68.00
+	Hs
		918874 RAB35_HUMAN (4-187): 1.09e-82: 244: 31.28		RAB1A_HUMAN (3-180): 1.3e-66: 204: 18.58
+	Mm
		918986 RAB35_MOUSE (4-187): 1.09e-82: 244: 31.28		RAB1A_MOUSE (3-180): 1.3e-66: 204: 18.58
+	Mm
		1161509 RAB35_MOUSE (4-187): 1.09e-82: 244: 31.28		RAB1B_MOUSE (5-180): 7.02e-66: 202: 18.23
+	Hs
		895024 RAB2A_HUMAN (4-183): 1.46e-75: 227: 32.97		ARF6_HUMAN (5-179): 2.19e-73: 219: 68.00
+	Zm
		73944 B4FAE1_MAIZE (4-187): 8.1e-78: 232: 32.82		B4FAE1_MAIZE (5-180): 9.68e-68: 206: 19.89
+	Hs
		350037 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		RAB1A_HUMAN (3-180): 1.3e-66: 204: 18.58
+	Hs
		895036 RAB2A_HUMAN (4-183): 1.46e-75: 227: 32.97		ARF1_HUMAN (1-181): 5.85e-68: 206: 100.00
+	Hs
		895026 RAB2A_HUMAN (4-183): 1.46e-75: 227: 32.97		RAB1A_HUMAN (3-180): 1.3e-66: 204: 18.58
+	Hs
		895264 RAB2A_HUMAN (4-183): 1.46e-75: 227: 32.97		RAB1B_HUMAN (5-180): 3.45e-66: 202: 18.23
+	Mm
		1321974 RAB13_MOUSE (4-188): 2.76e-75: 226: 35.05		RAB1B_MOUSE (5-180): 7.02e-66: 202: 18.23
+	Mm
		919000 RAB1A_MOUSE (4-187): 7.4e-74: 222: 34.36		RAB1B_MOUSE (5-180): 7.02e-66: 202: 18.23