HitPredict

Interactor 1: RASK (P01116)
GTPase KRas (EC 3.6.5.2) (K-Ras 2) (Ki-Ras) (c-K-ras) (c-Ki-ras) [Cleaved into: GTPase KRas, N-terminally processed]
Gene: KRAS

Interactor 2: EFNB1 (P98172)
Ephrin-B1 (EFL-3) (ELK ligand) (ELK-L) (EPH-related receptor tyrosine kinase ligand 2) (LERK-2) [Cleaved into: Ephrin-B1 C-terminal fragment (Ephrin-B1 CTF); Ephrin-B1 intracellular domain (Ephrin-B1 ICD)]
Gene: EFNB1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	30194290, 34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005886 - plasma membrane
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 189 Hs			1 346
+	Hs
		349244 RASH_HUMAN (1-188): 6.53e-87: 255: 86.77		EFNB1_HUMAN (1-346): 0: 538: 100.00
+	Hs
		348613 RASN_HUMAN (1-189): 2.37e-85: 251: 85.19		EFNB1_HUMAN (1-346): 0: 538: 100.00
+	Hs
		957839 RAB35_HUMAN (4-187): 1.09e-82: 244: 31.28		EFNB1_HUMAN (1-346): 0: 538: 100.00
+	Hs
		895039 RAB2A_HUMAN (4-183): 1.46e-75: 227: 32.97		EFNB1_HUMAN (1-346): 0: 538: 100.00
+	Hs
		914008 RB11A_HUMAN (4-184): 2.43e-72: 219: 33.88		EFNB1_HUMAN (1-346): 0: 538: 100.00
+	Hs
		349211 RASH_HUMAN (1-188): 6.53e-87: 255: 86.77		EFNB2_HUMAN (8-346): 1.88e-155: 441: 55.39
+	Hs
		348589 RASN_HUMAN (1-189): 2.37e-85: 251: 85.19		EFNB2_HUMAN (8-346): 1.88e-155: 441: 55.39
+	Hs
		856534 RAB35_HUMAN (4-187): 1.09e-82: 244: 31.28		EFNB2_HUMAN (8-346): 1.88e-155: 441: 55.39
+	Hs
		349998 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		EFNB2_HUMAN (8-346): 1.88e-155: 441: 55.39
+	Hs
		856516 RAB2A_HUMAN (4-183): 1.46e-75: 227: 32.97		EFNB2_HUMAN (8-346): 1.88e-155: 441: 55.39
+	Hs
		856521 RB11A_HUMAN (4-184): 2.43e-72: 219: 33.88		EFNB2_HUMAN (8-346): 1.88e-155: 441: 55.39
+	Hs
		349340 RASH_HUMAN (1-188): 6.53e-87: 255: 86.77		EFNB3_HUMAN (33-346): 6.4e-107: 318: 41.28
+	Hs
		348679 RASN_HUMAN (1-189): 2.37e-85: 251: 85.19		EFNB3_HUMAN (33-346): 6.4e-107: 318: 41.28
+	Hs
		350194 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		EFNB3_HUMAN (33-346): 6.4e-107: 318: 41.28