HitPredict

Interactor 1: RASK (P01116)
GTPase KRas (EC 3.6.5.2) (K-Ras 2) (Ki-Ras) (c-K-ras) (c-Ki-ras) [Cleaved into: GTPase KRas, N-terminally processed]
Gene: KRAS

Interactor 2: SPTB2 (Q01082)
Spectrin beta chain, non-erythrocytic 1 (Beta-II spectrin) (Fodrin beta chain) (Spectrin, non-erythroid beta chain 1)
Gene: SPTBN1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.60	0.640

Property	Details
Experiments	27684187, 30442766, 34079125
Identification Methods	affinity chromatography technology, proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0030036 - actin cytoskeleton organization
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 189 Hs			1 2364
+	Hs
		349252 RASH_HUMAN (1-188): 6.53e-87: 255: 86.77		SPTB2_HUMAN (1-2364): 0: 751: 100.00
+	Hs
		348621 RASN_HUMAN (1-189): 2.37e-85: 251: 85.19		SPTB2_HUMAN (1-2364): 0: 751: 100.00
+	Hs
		963331 RAB35_HUMAN (4-187): 1.09e-82: 244: 31.28		SPTB2_HUMAN (1-2364): 0: 751: 100.00
+	Hs
		349049 RASH_HUMAN (1-188): 6.53e-87: 255: 86.77		SPTA1_HUMAN (179-1394): 3.14e-92: 337: 19.60
+	Hs
		348458 RASN_HUMAN (1-189): 2.37e-85: 251: 85.19		SPTA1_HUMAN (179-1394): 3.14e-92: 337: 19.60
+	Hs
		349783 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		SPTA1_HUMAN (179-1394): 3.14e-92: 337: 19.60
+	Hs
		297805 RASN_HUMAN (1-189): 2.37e-85: 251: 85.19		K0754_HUMAN (210-1343): 2.52e-36: 154: 15.07
+	Hs
		297829 RAB35_HUMAN (4-187): 1.09e-82: 244: 31.28		K0754_HUMAN (210-1343): 2.52e-36: 154: 15.07
+	Hs
		297806 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		K0754_HUMAN (210-1343): 2.52e-36: 154: 15.07
+	Hs
		349308 RASH_HUMAN (1-188): 6.53e-87: 255: 86.77		SPTN1_HUMAN (152-1087): 9.93e-19: 96.3: 16.89
+	Hs
		974076 RAB35_HUMAN (4-187): 1.09e-82: 244: 31.28		DYST_HUMAN (537-1421): 8.42e-22: 106: 12.00
+	Hs
		348654 RASN_HUMAN (1-189): 2.37e-85: 251: 85.19		SPTN1_HUMAN (152-1087): 9.93e-19: 96.3: 16.89
+	Hs
		349327 RASH_HUMAN (1-188): 6.53e-87: 255: 86.77		PLEC_HUMAN (222-1144): 1.08e-16: 89.7: 11.59
+	Hs
		1045419 RAB35_HUMAN (4-187): 1.09e-82: 244: 31.28		SPTN1_HUMAN (152-1087): 9.93e-19: 96.3: 16.89
+	Hs
		809121 RAB35_HUMAN (4-187): 1.09e-82: 244: 31.28		UTRN_HUMAN (212-2073): 1e-17: 93.2: 10.02
+	Hs
		350095 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		DYST_HUMAN (537-1421): 8.42e-22: 106: 12.00
+	Hs
		164547 RASN_HUMAN (1-189): 2.37e-85: 251: 85.19		SPTN2_HUMAN (1661-2338): 1.76e-11: 72.4: 15.10
+	Hs
		349963 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		UTRN_HUMAN (212-2073): 1e-17: 93.2: 10.02
+	Hs
		164620 RAB35_HUMAN (4-187): 1.09e-82: 244: 31.28		SPTN2_HUMAN (1661-2338): 1.76e-11: 72.4: 15.10
+	Hs
		164548 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		SPTN2_HUMAN (1661-2338): 1.76e-11: 72.4: 15.10