HitPredict

Interactor 1: RASK (P01116)
GTPase KRas (EC 3.6.5.2) (K-Ras 2) (Ki-Ras) (c-K-ras) (c-Ki-ras) [Cleaved into: GTPase KRas, N-terminally processed]
Gene: KRAS

Interactor 2: AKA12 (Q02952)
A-kinase anchor protein 12 (AKAP-12) (A-kinase anchor protein 250 kDa) (AKAP 250) (Gravin) (Myasthenia gravis autoantigen)
Gene: AKAP12

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0005925 - focal adhesion
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 189 Hs			1 1782
+	Hs
		348627 RASN_HUMAN (1-189): 2.37e-85: 251: 85.19		AKA12_HUMAN (1-1782): 0: 676: 100.00
+	Hs
		973764 RAB35_HUMAN (4-187): 1.09e-82: 244: 31.28		AKA12_HUMAN (1-1782): 0: 676: 100.00
+	Hs
		895047 RAB2A_HUMAN (4-183): 1.46e-75: 227: 32.97		AKA12_HUMAN (1-1782): 0: 676: 100.00
+	Hs
		914019 RB11A_HUMAN (4-184): 2.43e-72: 219: 33.88		AKA12_HUMAN (1-1782): 0: 676: 100.00
+	Hs
		350405 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		TITIN_HUMAN (21-962): 3.34e-13: 77.6: 11.72
+	Hs
		350694 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		SRRM2_HUMAN (4-1096): 6.49e-11: 70: 7.25
+	Hs
		914253 RB11A_HUMAN (4-184): 2.43e-72: 219: 33.88		TITIN_HUMAN (21-962): 3.34e-13: 77.6: 11.72
+	Hs
		801060 RB11A_HUMAN (4-184): 2.43e-72: 219: 33.88		KI67_HUMAN (1-1782): 2.94e-11: 71.2: 11.31
+	Hs
		801050 RAP1B_HUMAN (1-165): 1.02e-62: 193: 57.49		KI67_HUMAN (1-1782): 2.94e-11: 71.2: 11.31