HitPredict

Interactor 1: RASK (P01116)
GTPase KRas (EC 3.6.5.2) (K-Ras 2) (Ki-Ras) (c-K-ras) (c-Ki-ras) [Cleaved into: GTPase KRas, N-terminally processed]
Gene: KRAS

Interactor 2: SNTB1 (Q13884)
Beta-1-syntrophin (59 kDa dystrophin-associated protein A1 basic component 1) (DAPA1B) (BSYN2) (Syntrophin-2) (Tax interaction protein 43) (TIP-43)
Gene: SNTB1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	30639242
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PDZ~Ras, PH~Ras
Common GO terms	GO:0005737 - cytoplasm GO:0005925 - focal adhesion
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 189 Hs			1 538
+	Hs
		159212 RAB35_HUMAN (4-187): 1.09e-82: 244: 31.28		CSKP_HUMAN (28-512): 1.27e-73: 253: 10.90
+	Hs
		159130 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		CSKP_HUMAN (28-512): 1.27e-73: 253: 10.90
+	Hs
		350623 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		PALS2_HUMAN (7-474): 7.86e-69: 232: 9.98
+	Hs
		349664 RASH_HUMAN (1-188): 6.53e-87: 255: 86.77		GOPC_HUMAN (83-258): 5.81e-30: 124: 31.64
+	Hs
		348940 RASN_HUMAN (1-189): 2.37e-85: 251: 85.19		GOPC_HUMAN (83-258): 5.81e-30: 124: 31.64
+	Hs
		349277 RASH_HUMAN (1-188): 6.53e-87: 255: 86.77		DLG1_HUMAN (77-203): 1.17e-21: 101: 33.33
+	Hs
		348639 RASN_HUMAN (1-189): 2.37e-85: 251: 85.19		DLG1_HUMAN (77-203): 1.17e-21: 101: 33.33
+	Hs
		895283 RAB2A_HUMAN (4-183): 1.46e-75: 227: 32.97		GOPC_HUMAN (83-258): 5.81e-30: 124: 31.64
+	Hs
		349543 RASH_HUMAN (1-188): 6.53e-87: 255: 86.77		DLG3_HUMAN (39-380): 6.2e-19: 92.7: 14.80
+	Hs
		1021495 RAB35_HUMAN (4-187): 1.09e-82: 244: 31.28		DLG1_HUMAN (77-203): 1.17e-21: 101: 33.33
+	Hs
		914375 RB11A_HUMAN (4-184): 2.43e-72: 219: 33.88		GOPC_HUMAN (83-258): 5.81e-30: 124: 31.64
+	Hs
		348876 RASN_HUMAN (1-189): 2.37e-85: 251: 85.19		MAGI1_HUMAN (26-271): 1.78e-16: 85.3: 16.00
+	Hs
		350124 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		DLG1_HUMAN (77-203): 1.17e-21: 101: 33.33
+	Hs
		895057 RAB2A_HUMAN (4-183): 1.46e-75: 227: 32.97		DLG1_HUMAN (77-203): 1.17e-21: 101: 33.33
+	Mm
		1143458 RAB14_MOUSE (4-184): 3.77e-72: 218: 29.51		DLG4_MOUSE (62-203): 1.24e-23: 107: 27.89
+	Hs
		350420 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		DLG3_HUMAN (39-380): 6.2e-19: 92.7: 14.80
+	Hs
		914039 RB11A_HUMAN (4-184): 2.43e-72: 219: 33.88		DLG1_HUMAN (77-203): 1.17e-21: 101: 33.33
+	Hs
		350465 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		MAGI1_HUMAN (26-271): 1.78e-16: 85.3: 16.00