HitPredict

Interactor 1: RASK (P01116)
GTPase KRas (EC 3.6.5.2) (K-Ras 2) (Ki-Ras) (c-K-ras) (c-Ki-ras) [Cleaved into: GTPase KRas, N-terminally processed]
Gene: KRAS

Interactor 2: DSG2 (Q14126)
Desmoglein-2 (Cadherin family member 5) (HDGC)
Gene: DSG2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	30194290, 34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 189 Hs			1 1118
+	Hs
		349315 RASH_HUMAN (1-188): 6.53e-87: 255: 86.77		DSG2_HUMAN (1-1118): 0: 1174: 100.00
+	Hs
		348660 RASN_HUMAN (1-189): 2.37e-85: 251: 85.19		DSG2_HUMAN (1-1118): 0: 1174: 100.00
+	Hs
		1048587 RAB35_HUMAN (4-187): 1.09e-82: 244: 31.28		DSG2_HUMAN (1-1118): 0: 1174: 100.00
+	Hs
		895075 RAB2A_HUMAN (4-183): 1.46e-75: 227: 32.97		DSG2_HUMAN (1-1118): 0: 1174: 100.00
+	Hs
		914063 RB11A_HUMAN (4-184): 2.43e-72: 219: 33.88		DSG2_HUMAN (1-1118): 0: 1174: 100.00
+	Hs
		349094 RASH_HUMAN (1-188): 6.53e-87: 255: 86.77		CADH1_HUMAN (22-670): 0: 577: 31.67
+	Hs
		349835 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		CADH1_HUMAN (22-670): 0: 577: 31.67
+	Hs
		521847 RAB1A_HUMAN (4-187): 7.4e-74: 222: 34.36		CADH1_HUMAN (22-670): 0: 577: 31.67
+	Cl
		94527 RAB1A_CANLF (4-187): 7.4e-74: 222: 34.36		CADH1_CANLF (30-670): 0: 572: 30.64
+	Hs
		349259 RASH_HUMAN (1-188): 6.53e-87: 255: 86.77		DSC2_HUMAN (28-494): 8.1e-51: 196: 16.90
+	Hs
		348626 RASN_HUMAN (1-189): 2.37e-85: 251: 85.19		DSC2_HUMAN (28-494): 8.1e-51: 196: 16.90
+	Hs
		971013 RAB35_HUMAN (4-187): 1.09e-82: 244: 31.28		DSC2_HUMAN (28-494): 8.1e-51: 196: 16.90
+	Hs
		350090 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		DSC2_HUMAN (28-494): 8.1e-51: 196: 16.90
+	Hs
		895046 RAB2A_HUMAN (4-183): 1.46e-75: 227: 32.97		DSC2_HUMAN (28-494): 8.1e-51: 196: 16.90
+	Hs
		914018 RB11A_HUMAN (4-184): 2.43e-72: 219: 33.88		DSC2_HUMAN (28-494): 8.1e-51: 196: 16.90
+	Hs
		349322 RASH_HUMAN (1-188): 6.53e-87: 255: 86.77		DSC3_HUMAN (28-361): 8.23e-29: 126: 16.86
+	Hs
		348666 RASN_HUMAN (1-189): 2.37e-85: 251: 85.19		DSC3_HUMAN (28-361): 8.23e-29: 126: 16.86
+	Hs
		350172 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		DSC3_HUMAN (28-361): 8.23e-29: 126: 16.86