HitPredict

Interactor 1: RASK (P01116)
GTPase KRas (EC 3.6.5.2) (K-Ras 2) (Ki-Ras) (c-K-ras) (c-Ki-ras) [Cleaved into: GTPase KRas, N-terminally processed]
Gene: KRAS

Interactor 2: SCRIB (Q14160)
Protein scribble homolog (Scribble) (hScrib) (Protein LAP4)
Gene: SCRIB

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	1.00	0.754

Property	Details
Experiments	30442766, 34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PDZ~Ras
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 189 Hs			1 1630
+	Hs
		349319 RASH_HUMAN (1-188): 6.53e-87: 255: 86.77		SCRIB_HUMAN (1-1630): 0: 978: 100.00
+	Hs
		348663 RASN_HUMAN (1-189): 2.37e-85: 251: 85.19		SCRIB_HUMAN (1-1630): 0: 978: 100.00
+	Hs
		1049954 RAB35_HUMAN (4-187): 1.09e-82: 244: 31.28		SCRIB_HUMAN (1-1630): 0: 978: 100.00
+	Hs
		914066 RB11A_HUMAN (4-184): 2.43e-72: 219: 33.88		SCRIB_HUMAN (1-1630): 0: 978: 100.00
+	Hs
		349737 RASH_HUMAN (1-188): 6.53e-87: 255: 86.77		SHOC2_HUMAN (1-377): 1.41e-94: 320: 30.45
+	Ce
		612369 LET60_CAEEL (1-189): 1.63e-85: 251: 74.60		SHOC2_CAEEL (1-387): 2.9e-90: 307: 28.13
+	Hs
		350693 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		SHOC2_HUMAN (1-377): 1.41e-94: 320: 30.45
+	Hs
		350499 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		LRRC1_HUMAN (1-277): 7.16e-72: 252: 31.77
+	Hs
		349543 RASH_HUMAN (1-188): 6.53e-87: 255: 86.77		DLG3_HUMAN (724-947): 1.74e-19: 97.4: 31.23
+	Hs
		349277 RASH_HUMAN (1-188): 6.53e-87: 255: 86.77		DLG1_HUMAN (687-910): 4.67e-15: 82.9: 24.68
+	Hs
		348639 RASN_HUMAN (1-189): 2.37e-85: 251: 85.19		DLG1_HUMAN (687-910): 4.67e-15: 82.9: 24.68
+	Hs
		349581 RASH_HUMAN (1-188): 6.53e-87: 255: 86.77		ERBIN_HUMAN (816-952): 8.76e-12: 72.8: 28.06
+	Hs
		1021495 RAB35_HUMAN (4-187): 1.09e-82: 244: 31.28		DLG1_HUMAN (687-910): 4.67e-15: 82.9: 24.68
+	Hs
		350420 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		DLG3_HUMAN (724-947): 1.74e-19: 97.4: 31.23
+	Hs
		348879 RASN_HUMAN (1-189): 2.37e-85: 251: 85.19		ERBIN_HUMAN (816-952): 8.76e-12: 72.8: 28.06
+	Hs
		1070354 RAB35_HUMAN (4-187): 1.09e-82: 244: 31.28		ERBIN_HUMAN (816-952): 8.76e-12: 72.8: 28.06
+	Hs
		350124 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		DLG1_HUMAN (687-910): 4.67e-15: 82.9: 24.68
+	Hs
		895057 RAB2A_HUMAN (4-183): 1.46e-75: 227: 32.97		DLG1_HUMAN (687-910): 4.67e-15: 82.9: 24.68
+	Hs
		914039 RB11A_HUMAN (4-184): 2.43e-72: 219: 33.88		DLG1_HUMAN (687-910): 4.67e-15: 82.9: 24.68
+	Hs
		350468 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		ERBIN_HUMAN (816-952): 8.76e-12: 72.8: 28.06