HitPredict

Interactor 1: RASK (P01116)
GTPase KRas (EC 3.6.5.2) (K-Ras 2) (Ki-Ras) (c-K-ras) (c-Ki-ras) [Cleaved into: GTPase KRas, N-terminally processed]
Gene: KRAS

Interactor 2: ANKS6 (Q68DC2)
Ankyrin repeat and SAM domain-containing protein 6 (Ankyrin repeat domain-containing protein 14) (SamCystin) (Sterile alpha motif domain-containing protein 6) (SAM domain-containing protein 6)
Gene: ANKS6

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Ank~Ras, Ank_2~Ras
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 189 Hs			1 871
+	Hs
		349398 RASH_HUMAN (1-188): 6.53e-87: 255: 86.77		ANKS6_HUMAN (1-871): 0: 568: 100.00
+	Dm
		1248518 Q962I2_DROME (4-178): 1.03e-60: 189: 51.14		Q8SWY2_DROME (9-844): 1.09e-121: 394: 16.03
+	Hs
		349000 RASN_HUMAN (1-189): 2.37e-85: 251: 85.19		KDIS_HUMAN (51-482): 1.86e-92: 322: 23.50
+	Hs
		1070450 RAB35_HUMAN (4-187): 1.09e-82: 244: 31.28		KDIS_HUMAN (51-482): 1.86e-92: 322: 23.50
+	Hs
		350674 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		KDIS_HUMAN (51-482): 1.86e-92: 322: 23.50
+	Hs
		895318 RAB2A_HUMAN (4-183): 1.46e-75: 227: 32.97		KDIS_HUMAN (51-482): 1.86e-92: 322: 23.50
+	Hs
		914450 RB11A_HUMAN (4-184): 2.43e-72: 219: 33.88		KDIS_HUMAN (51-482): 1.86e-92: 322: 23.50
+	Hs
		349001 RASN_HUMAN (1-189): 2.37e-85: 251: 85.19		ANR50_HUMAN (3-363): 6.58e-73: 263: 20.78
+	Hs
		350675 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		ANR50_HUMAN (3-363): 6.58e-73: 263: 20.78
+	Hs
		349253 RASH_HUMAN (1-188): 6.53e-87: 255: 86.77		ANK2_HUMAN (3-298): 1.33e-63: 236: 23.31
+	Hs
		350083 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		ANK2_HUMAN (3-298): 1.33e-63: 236: 23.31
+	Hs
		1021405 RAB35_HUMAN (4-187): 1.09e-82: 244: 31.28		ANK3_HUMAN (293-583): 6.94e-34: 143: 15.31
+	Hs
		350123 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		ANK3_HUMAN (293-583): 6.94e-34: 143: 15.31
+	Dm
		65552 RALA_DROME (4-182): 3.4e-60: 187: 52.22		A8JNM5_DROME (266-576): 1.75e-34: 145: 13.85
+	Mm
		71299 RAB13_MOUSE (4-188): 2.76e-75: 226: 35.05		ANR44_MOUSE (363-655): 1.96e-13: 76.5: 12.16