HitPredict

Interactor 1: RASK (P01116)
GTPase KRas (EC 3.6.5.2) (K-Ras 2) (Ki-Ras) (c-K-ras) (c-Ki-ras) [Cleaved into: GTPase KRas, N-terminally processed]
Gene: KRAS

Interactor 2: MICA3 (Q7RTP6)
[F-actin]-monooxygenase MICAL3 (EC 1.14.13.225) (Molecule interacting with CasL protein 3) (MICAL-3)
Gene: MICAL3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	1.00	0.754

Property	Details
Experiments	30639242, 34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Ras~bMERB_dom
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 189 Hs			1 2002
+	Hs
		1070268 RAB35_HUMAN (4-187): 1.09e-82: 244: 31.28		MICA3_HUMAN (1-2002): 0: 1314: 100.00
+	Hs
		918915 RAB1A_HUMAN (4-187): 7.4e-74: 222: 34.36		MICA1_HUMAN (8-1107): 0: 950: 37.63
+	Hs
		1255762 RAB1B_HUMAN (4-187): 1.21e-73: 221: 32.47		MICA1_HUMAN (8-1107): 0: 950: 37.63
+	Hs
		349252 RASH_HUMAN (1-188): 6.53e-87: 255: 86.77		SPTB2_HUMAN (433-1059): 2.31e-85: 314: 16.56
+	Hs
		348621 RASN_HUMAN (1-189): 2.37e-85: 251: 85.19		SPTB2_HUMAN (433-1059): 2.31e-85: 314: 16.56
+	Hs
		963331 RAB35_HUMAN (4-187): 1.09e-82: 244: 31.28		SPTB2_HUMAN (433-1059): 2.31e-85: 314: 16.56
+	Hs
		164547 RASN_HUMAN (1-189): 2.37e-85: 251: 85.19		SPTN2_HUMAN (433-1216): 1.38e-79: 295: 14.86
+	Hs
		350082 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		SPTB2_HUMAN (433-1059): 2.31e-85: 314: 16.56
+	Hs
		895043 RAB2A_HUMAN (4-183): 1.46e-75: 227: 32.97		SPTB2_HUMAN (433-1059): 2.31e-85: 314: 16.56
+	Hs
		164620 RAB35_HUMAN (4-187): 1.09e-82: 244: 31.28		SPTN2_HUMAN (433-1216): 1.38e-79: 295: 14.86
+	Hs
		164548 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		SPTN2_HUMAN (433-1216): 1.38e-79: 295: 14.86
+	Hs
		164591 RAB2A_HUMAN (4-183): 1.46e-75: 227: 32.97		SPTN2_HUMAN (433-1216): 1.38e-79: 295: 14.86
+	Mm
		1112011 RAB13_MOUSE (4-188): 2.76e-75: 226: 35.05		MILK2_MOUSE (518-1453): 5.89e-67: 249: 17.00
+	Hs
		348801 RASN_HUMAN (1-189): 2.37e-85: 251: 85.19		EHBP1_HUMAN (520-762): 2.11e-37: 156: 22.53
+	Hs
		1070306 RAB35_HUMAN (4-187): 1.09e-82: 244: 31.28		EHBP1_HUMAN (520-762): 2.11e-37: 156: 22.53
+	Hs
		350362 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		EHBP1_HUMAN (520-762): 2.11e-37: 156: 22.53
+	Hs
		349475 RASH_HUMAN (1-188): 6.53e-87: 255: 86.77		MILK1_HUMAN (715-885): 2.96e-16: 87.2: 21.14
+	Hs
		1070295 RAB35_HUMAN (4-187): 1.09e-82: 244: 31.28		MILK1_HUMAN (715-885): 2.96e-16: 87.2: 21.14
+	Hs
		349327 RASH_HUMAN (1-188): 6.53e-87: 255: 86.77		PLEC_HUMAN (619-1989): 3.73e-11: 71.1: 10.87
+	Hs
		350338 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		MILK1_HUMAN (715-885): 2.96e-16: 87.2: 21.14