HitPredict

Interactor 1: RASK (P01116)
GTPase KRas (EC 3.6.5.2) (K-Ras 2) (Ki-Ras) (c-K-ras) (c-Ki-ras) [Cleaved into: GTPase KRas, N-terminally processed]
Gene: KRAS

Interactor 2: THOC6 (Q86W42)
THO complex subunit 6 homolog (Functional spliceosome-associated protein 35) (fSAP35) (WD repeat-containing protein 58)
Gene: THOC6

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	27684187
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 189 Hs			1 341
+	Hs
		349546 RASH_HUMAN (1-188): 6.53e-87: 255: 86.77		FBXW7_HUMAN (1-149): 4.03e-22: 99.3: 7.38
+	Hs
		1070247 RAB35_HUMAN (4-187): 1.09e-82: 244: 31.28		A16L1_HUMAN (65-330): 1.22e-16: 82.9: 15.39
+	Mm
		1161506 RAB35_MOUSE (4-187): 1.09e-82: 244: 31.28		A16L1_MOUSE (13-330): 1.42e-15: 79.4: 16.31
+	Hs
		350249 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		A16L1_HUMAN (65-330): 1.22e-16: 82.9: 15.39
+	Mm
		699622 RASK_MOUSE (1-189): 4.5e-77: 230: 98.94		A16L1_MOUSE (13-330): 1.42e-15: 79.4: 16.31
+	Hs
		1146825 RAB1B_HUMAN (4-187): 1.21e-73: 221: 32.47		A16L1_HUMAN (65-330): 1.22e-16: 82.9: 15.39
+	Hs
		914135 RB11A_HUMAN (4-184): 2.43e-72: 219: 33.88		A16L1_HUMAN (65-330): 1.22e-16: 82.9: 15.39
+	Hs
		903100 RAB1A_HUMAN (4-187): 7.4e-74: 222: 34.36		WDR5_HUMAN (1-103): 1.25e-14: 75.4: 13.76
+	Hs
		903508 RAB1B_HUMAN (4-187): 1.21e-73: 221: 32.47		WDR5_HUMAN (1-103): 1.25e-14: 75.4: 13.76
+	Hs
		919616 RAP1A_HUMAN (1-165): 7.83e-63: 194: 58.08		GBB1_HUMAN (117-339): 5.07e-23: 99.7: 12.04
+	Hs
		896603 RAB14_HUMAN (4-184): 3.77e-72: 218: 29.51		WDR5_HUMAN (1-103): 1.25e-14: 75.4: 13.76
+	Sc
		350806 RAS2_YEAST (3-164): 2.5e-58: 187: 64.42		TAF5_YEAST (160-330): 7.47e-12: 68.5: 10.47