HitPredict

Interactor 1: RASK (P01116)
GTPase KRas (EC 3.6.5.2) (K-Ras 2) (Ki-Ras) (c-K-ras) (c-Ki-ras) [Cleaved into: GTPase KRas, N-terminally processed]
Gene: KRAS

Interactor 2: ZDH17 (Q8IUH5)
Palmitoyltransferase ZDHHC17 (EC 2.3.1.225) (Acyltransferase ZDHHC17) (EC 2.3.1.-) (DHHC domain-containing cysteine-rich protein 17) (DHHC17) (Huntingtin yeast partner H) (Huntingtin-interacting protein 14) (HIP-14) (Huntingtin-interacting protein 3) (HIP-3) (Huntingtin-interacting protein H) (Putative MAPK-activating protein PM11) (Putative NF-kappa-B-activating protein 205) (Zinc finger DHHC domain-containing protein 17)
Gene: ZDHHC17

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.48	1.00	0.698

Property	Details
Experiments	24705354
Identification Methods	two hybrid, two hybrid array
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	Ank_2~Ras
Common GO terms	GO:0000139 - Golgi membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 189 Hs			1 632
+	Hs
		349253 RASH_HUMAN (1-188): 6.53e-87: 255: 86.77		ANK2_HUMAN (2-451): 6.06e-82: 284: 17.14
+	Hs
		1021405 RAB35_HUMAN (4-187): 1.09e-82: 244: 31.28		ANK3_HUMAN (2-438): 1.56e-79: 277: 17.73
+	Hs
		350083 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		ANK2_HUMAN (2-451): 6.06e-82: 284: 17.14
+	Hs
		350123 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		ANK3_HUMAN (2-438): 1.56e-79: 277: 17.73
+	Hs
		349000 RASN_HUMAN (1-189): 2.37e-85: 251: 85.19		KDIS_HUMAN (2-403): 1.47e-66: 239: 14.82
+	Hs
		1070450 RAB35_HUMAN (4-187): 1.09e-82: 244: 31.28		KDIS_HUMAN (2-403): 1.47e-66: 239: 14.82
+	Hs
		350674 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		KDIS_HUMAN (2-403): 1.47e-66: 239: 14.82
+	Hs
		895318 RAB2A_HUMAN (4-183): 1.46e-75: 227: 32.97		KDIS_HUMAN (2-403): 1.47e-66: 239: 14.82
+	Hs
		349001 RASN_HUMAN (1-189): 2.37e-85: 251: 85.19		ANR50_HUMAN (71-327): 4.74e-53: 198: 23.89
+	Mm
		71299 RAB13_MOUSE (4-188): 2.76e-75: 226: 35.05		ANR44_MOUSE (2-290): 3.22e-59: 216: 19.53
+	Hs
		350675 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		ANR50_HUMAN (71-327): 4.74e-53: 198: 23.89
+	Hs
		349212 RASH_HUMAN (1-188): 6.53e-87: 255: 86.77		DAPK1_HUMAN (127-398): 2.56e-34: 142: 17.15
+	Hs
		348762 RASN_HUMAN (1-189): 2.37e-85: 251: 85.19		ZDH13_HUMAN (2-175): 2.04e-31: 131: 16.95
+	Hs
		349624 RASH_HUMAN (1-188): 6.53e-87: 255: 86.77		ZDHC5_HUMAN (370-594): 3.11e-18: 90.9: 29.79
+	Hs
		349748 RASH_HUMAN (1-188): 6.53e-87: 255: 86.77		ZDHC9_HUMAN (361-612): 1.42e-18: 89.7: 26.79
+	Hs
		348908 RASN_HUMAN (1-189): 2.37e-85: 251: 85.19		ZDHC5_HUMAN (370-594): 3.11e-18: 90.9: 29.79
+	Hs
		349022 RASN_HUMAN (1-189): 2.37e-85: 251: 85.19		ZDHC9_HUMAN (361-612): 1.42e-18: 89.7: 26.79
+	Hs
		1070383 RAB35_HUMAN (4-187): 1.09e-82: 244: 31.28		ZDHC5_HUMAN (370-594): 3.11e-18: 90.9: 29.79
+	Hs
		350522 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		ZDHC5_HUMAN (370-594): 3.11e-18: 90.9: 29.79
+	Hs
		895257 RAB2A_HUMAN (4-183): 1.46e-75: 227: 32.97		ZDHC5_HUMAN (370-594): 3.11e-18: 90.9: 29.79