HitPredict

Interactor 1: RASK (P01116)
GTPase KRas (EC 3.6.5.2) (K-Ras 2) (Ki-Ras) (c-K-ras) (c-Ki-ras) [Cleaved into: GTPase KRas, N-terminally processed]
Gene: KRAS

Interactor 2: RHG12 (Q8IWW6)
Rho GTPase-activating protein 12 (Rho-type GTPase-activating protein 12)
Gene: ARHGAP12

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PH~Ras, Ras~RhoGAP
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 189 Hs			1 846
+	Hs
		349384 RASH_HUMAN (1-188): 6.53e-87: 255: 86.77		RHG21_HUMAN (78-846): 3.01e-97: 336: 21.24
+	Hs
		1070234 RAB35_HUMAN (4-187): 1.09e-82: 244: 31.28		RHG21_HUMAN (78-846): 3.01e-97: 336: 21.24
+	Hs
		350234 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		RHG21_HUMAN (78-846): 3.01e-97: 336: 21.24
+	Hs
		895119 RAB2A_HUMAN (4-183): 1.46e-75: 227: 32.97		RHG21_HUMAN (78-846): 3.01e-97: 336: 21.24
+	Hs
		895065 RAB2A_HUMAN (4-183): 1.46e-75: 227: 32.97		MYO9B_HUMAN (52-840): 3.46e-94: 327: 17.69
+	Hs
		350527 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		RHG39_HUMAN (92-844): 1.04e-80: 283: 14.42
+	Hs
		64708 RAB35_HUMAN (4-187): 1.09e-82: 244: 31.28		RHG32_HUMAN (603-844): 6.16e-73: 263: 30.00
+	Hs
		349535 RASH_HUMAN (1-188): 6.53e-87: 255: 86.77		ARAP2_HUMAN (223-844): 7.19e-69: 251: 14.73
+	Hs
		349280 RASH_HUMAN (1-188): 6.53e-87: 255: 86.77		ABR_HUMAN (301-846): 3.7e-70: 250: 19.86
+	Hs
		49624 RASH_HUMAN (1-188): 6.53e-87: 255: 86.77		RHG10_HUMAN (387-844): 1.32e-70: 250: 19.30
+	Hs
		64637 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		RHG32_HUMAN (603-844): 6.16e-73: 263: 30.00
+	Hs
		253300 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		SRGP2_HUMAN (534-845): 1.45e-69: 251: 22.40
+	Hs
		350406 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		ARAP2_HUMAN (223-844): 7.19e-69: 251: 14.73
+	Hs
		350207 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		RHG31_HUMAN (634-844): 5.53e-63: 233: 31.05
+	Hs
		506558 RAB2A_HUMAN (4-183): 1.46e-75: 227: 32.97		BCR_HUMAN (632-819): 7.58e-25: 113: 39.27