HitPredict

Interactor 1: RASK (P01116)
GTPase KRas (EC 3.6.5.2) (K-Ras 2) (Ki-Ras) (c-K-ras) (c-Ki-ras) [Cleaved into: GTPase KRas, N-terminally processed]
Gene: KRAS

Interactor 2: UNC5B (Q8IZJ1)
Netrin receptor UNC5B (Protein unc-5 homolog 2) (Protein unc-5 homolog B) (p53-regulated receptor for death and life protein 1) (p53RDL1)
Gene: UNC5B

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	30194290, 34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0043524 - negative regulation of neuron apoptotic process
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 189 Hs			1 945
+	Hs
		349465 RASH_HUMAN (1-188): 6.53e-87: 255: 86.77		UNC5B_HUMAN (1-945): 0: 962: 100.00
+	Hs
		348774 RASN_HUMAN (1-189): 2.37e-85: 251: 85.19		UNC5B_HUMAN (1-945): 0: 962: 100.00
+	Hs
		1070289 RAB35_HUMAN (4-187): 1.09e-82: 244: 31.28		UNC5B_HUMAN (1-945): 0: 962: 100.00
+	Hs
		306915 RAB35_HUMAN (4-187): 1.09e-82: 244: 31.28		UNC5C_HUMAN (32-944): 0: 864: 63.75
+	Hs
		306898 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		UNC5C_HUMAN (32-944): 0: 864: 63.75
+	Hs
		306909 RB11A_HUMAN (4-184): 2.43e-72: 219: 33.88		UNC5C_HUMAN (32-944): 0: 864: 63.75
+	Hs
		350106 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		ZO1_HUMAN (405-656): 2.76e-51: 198: 20.63
+	Hs
		349775 RASH_HUMAN (1-188): 6.53e-87: 255: 86.77		ROBO1_HUMAN (2-257): 1.06e-41: 168: 17.16
+	Hs
		349043 RASN_HUMAN (1-189): 2.37e-85: 251: 85.19		ROBO1_HUMAN (2-257): 1.06e-41: 168: 17.16
+	Hs
		1070491 RAB35_HUMAN (4-187): 1.09e-82: 244: 31.28		ROBO1_HUMAN (2-257): 1.06e-41: 168: 17.16
+	Hs
		350746 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		ROBO1_HUMAN (2-257): 1.06e-41: 168: 17.16
+	Hs
		914506 RB11A_HUMAN (4-184): 2.43e-72: 219: 33.88		ROBO1_HUMAN (2-257): 1.06e-41: 168: 17.16
+	Hs
		350572 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		ROBO2_HUMAN (9-177): 5.33e-19: 95.1: 11.41