HitPredict

Interactor 1: RASK (P01116)
GTPase KRas (EC 3.6.5.2) (K-Ras 2) (Ki-Ras) (c-K-ras) (c-Ki-ras) [Cleaved into: GTPase KRas, N-terminally processed]
Gene: KRAS

Interactor 2: PALS1 (Q8N3R9)
Protein PALS1 (MAGUK p55 subfamily member 5) (Membrane protein, palmitoylated 5) (Protein associated with Lin-7 1)
Gene: PALS1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	30639242
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PDZ~Ras
Common GO terms	GO:0005737 - cytoplasm GO:0005886 - plasma membrane GO:0010467 - gene expression
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 189 Hs			1 675
+	Hs
		349476 RASH_HUMAN (1-188): 6.53e-87: 255: 86.77		PALS1_HUMAN (1-675): 0: 561: 100.00
+	Hs
		1070296 RAB35_HUMAN (4-187): 1.09e-82: 244: 31.28		PALS1_HUMAN (1-675): 0: 561: 100.00
+	Hs
		159212 RAB35_HUMAN (4-187): 1.09e-82: 244: 31.28		CSKP_HUMAN (9-674): 7.61e-136: 423: 25.80
+	Hs
		349277 RASH_HUMAN (1-188): 6.53e-87: 255: 86.77		DLG1_HUMAN (7-672): 1.81e-129: 406: 21.58
+	Hs
		348639 RASN_HUMAN (1-189): 2.37e-85: 251: 85.19		DLG1_HUMAN (7-672): 1.81e-129: 406: 21.58
+	Hs
		350623 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		PALS2_HUMAN (134-674): 6.92e-142: 426: 34.66
+	Hs
		159130 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		CSKP_HUMAN (9-674): 7.61e-136: 423: 25.80
+	Hs
		1021495 RAB35_HUMAN (4-187): 1.09e-82: 244: 31.28		DLG1_HUMAN (7-672): 1.81e-129: 406: 21.58
+	Hs
		349383 RASH_HUMAN (1-188): 6.53e-87: 255: 86.77		MPP7_HUMAN (122-674): 6.17e-127: 389: 36.06
+	Hs
		348711 RASN_HUMAN (1-189): 2.37e-85: 251: 85.19		MPP7_HUMAN (122-674): 6.17e-127: 389: 36.06
+	Hs
		349246 RASH_HUMAN (1-188): 6.53e-87: 255: 86.77		EM55_HUMAN (190-674): 1.63e-125: 382: 29.36
+	Hs
		350124 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		DLG1_HUMAN (7-672): 1.81e-129: 406: 21.58
+	Hs
		1070233 RAB35_HUMAN (4-187): 1.09e-82: 244: 31.28		MPP7_HUMAN (122-674): 6.17e-127: 389: 36.06
+	Hs
		348614 RASN_HUMAN (1-189): 2.37e-85: 251: 85.19		EM55_HUMAN (190-674): 1.63e-125: 382: 29.36
+	Hs
		895057 RAB2A_HUMAN (4-183): 1.46e-75: 227: 32.97		DLG1_HUMAN (7-672): 1.81e-129: 406: 21.58
+	Hs
		350231 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		MPP7_HUMAN (122-674): 6.17e-127: 389: 36.06
+	Hs
		895117 RAB2A_HUMAN (4-183): 1.46e-75: 227: 32.97		MPP7_HUMAN (122-674): 6.17e-127: 389: 36.06
+	Hs
		350077 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		EM55_HUMAN (190-674): 1.63e-125: 382: 29.36
+	Hs
		349543 RASH_HUMAN (1-188): 6.53e-87: 255: 86.77		DLG3_HUMAN (256-326): 7.18e-12: 70.8: 20.25
+	Hs
		350420 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		DLG3_HUMAN (256-326): 7.18e-12: 70.8: 20.25