HitPredict

Interactor 1: RASK (P01116)
GTPase KRas (EC 3.6.5.2) (K-Ras 2) (Ki-Ras) (c-K-ras) (c-Ki-ras) [Cleaved into: GTPase KRas, N-terminally processed]
Gene: KRAS

Interactor 2: PARD3 (Q8TEW0)
Partitioning defective 3 homolog (PAR-3) (PARD-3) (Atypical PKC isotype-specific-interacting protein) (ASIP) (CTCL tumor antigen se2-5) (PAR3-alpha)
Gene: PARD3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	1.00	0.754

Property	Details
Experiments	30639242, 34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PDZ~Ras
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 189 Hs			1 1356
+	Hs
		349520 RASH_HUMAN (1-188): 6.53e-87: 255: 86.77		PARD3_HUMAN (1-1356): 0: 709: 100.00
+	Hs
		1070320 RAB35_HUMAN (4-187): 1.09e-82: 244: 31.28		PARD3_HUMAN (1-1356): 0: 709: 100.00
+	Hs
		349002 RASN_HUMAN (1-189): 2.37e-85: 251: 85.19		NEB1_HUMAN (36-1074): 1.37e-60: 229: 11.36
+	Hs
		1070451 RAB35_HUMAN (4-187): 1.09e-82: 244: 31.28		NEB1_HUMAN (36-1074): 1.37e-60: 229: 11.36
+	Hs
		350676 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		NEB1_HUMAN (36-1074): 1.37e-60: 229: 11.36
+	Hs
		895319 RAB2A_HUMAN (4-183): 1.46e-75: 227: 32.97		NEB1_HUMAN (36-1074): 1.37e-60: 229: 11.36
+	Hs
		349543 RASH_HUMAN (1-188): 6.53e-87: 255: 86.77		DLG3_HUMAN (556-1119): 1.21e-27: 123: 13.01
+	Hs
		350420 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		DLG3_HUMAN (556-1119): 1.21e-27: 123: 13.01
+	Hs
		349510 RASH_HUMAN (1-188): 6.53e-87: 255: 86.77		INADL_HUMAN (28-397): 1.09e-15: 85.1: 11.14
+	Hs
		348876 RASN_HUMAN (1-189): 2.37e-85: 251: 85.19		MAGI1_HUMAN (354-780): 1.36e-16: 88.1: 14.16
+	Hs
		1020162 RAB35_HUMAN (4-187): 1.09e-82: 244: 31.28		PTN13_HUMAN (39-368): 1.59e-16: 88.1: 12.50
+	Hs
		349319 RASH_HUMAN (1-188): 6.53e-87: 255: 86.77		SCRIB_HUMAN (66-355): 5.59e-09: 63.1: 12.75
+	Hs
		350121 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		PTN13_HUMAN (39-368): 1.59e-16: 88.1: 12.50
+	Hs
		350465 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		MAGI1_HUMAN (354-780): 1.36e-16: 88.1: 14.16
+	Hs
		348663 RASN_HUMAN (1-189): 2.37e-85: 251: 85.19		SCRIB_HUMAN (66-355): 5.59e-09: 63.1: 12.75
+	Hs
		350374 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		INADL_HUMAN (28-397): 1.09e-15: 85.1: 11.14
+	Hs
		1049954 RAB35_HUMAN (4-187): 1.09e-82: 244: 31.28		SCRIB_HUMAN (66-355): 5.59e-09: 63.1: 12.75
+	Hs
		350106 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		ZO1_HUMAN (271-586): 1.19e-11: 72: 14.06
+	Hs
		350166 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		SCRIB_HUMAN (66-355): 5.59e-09: 63.1: 12.75
+	Hs
		914066 RB11A_HUMAN (4-184): 2.43e-72: 219: 33.88		SCRIB_HUMAN (66-355): 5.59e-09: 63.1: 12.75