HitPredict

Interactor 1: RASK (P01116)
GTPase KRas (EC 3.6.5.2) (K-Ras 2) (Ki-Ras) (c-K-ras) (c-Ki-ras) [Cleaved into: GTPase KRas, N-terminally processed]
Gene: KRAS

Interactor 2: NDRG1 (Q92597)
Protein NDRG1 (Differentiation-related gene 1 protein) (DRG-1) (N-myc downstream-regulated gene 1 protein) (Nickel-specific induction protein Cap43) (Reducing agents and tunicamycin-responsive protein) (RTP) (Rit42)
Gene: NDRG1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	30194290, 34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005886 - plasma membrane
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 189 Hs			1 394
+	Hs
		349537 RASH_HUMAN (1-188): 6.53e-87: 255: 86.77		NDRG1_HUMAN (1-394): 0: 629: 100.00
+	Hs
		348832 RASN_HUMAN (1-189): 2.37e-85: 251: 85.19		NDRG1_HUMAN (1-394): 0: 629: 100.00
+	Hs
		1070330 RAB35_HUMAN (4-187): 1.09e-82: 244: 31.28		NDRG1_HUMAN (1-394): 0: 629: 100.00
+	Hs
		895212 RAB2A_HUMAN (4-183): 1.46e-75: 227: 32.97		NDRG1_HUMAN (1-394): 0: 629: 100.00
+	Hs
		914258 RB11A_HUMAN (4-184): 2.43e-72: 219: 33.88		NDRG1_HUMAN (1-394): 0: 629: 100.00
+	Hs
		349704 RASH_HUMAN (1-188): 6.53e-87: 255: 86.77		NDRG3_HUMAN (4-368): 7.69e-179: 503: 63.61
+	Hs
		348985 RASN_HUMAN (1-189): 2.37e-85: 251: 85.19		NDRG3_HUMAN (4-368): 7.69e-179: 503: 63.61
+	Hs
		1070440 RAB35_HUMAN (4-187): 1.09e-82: 244: 31.28		NDRG3_HUMAN (4-368): 7.69e-179: 503: 63.61
+	Hs
		350650 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		NDRG3_HUMAN (4-368): 7.69e-179: 503: 63.61