HitPredict

Interactor 1: RASK (P01116)
GTPase KRas (EC 3.6.5.2) (K-Ras 2) (Ki-Ras) (c-K-ras) (c-Ki-ras) [Cleaved into: GTPase KRas, N-terminally processed]
Gene: KRAS

Interactor 2: US6NL (Q92738)
USP6 N-terminal-like protein (Related to the N-terminus of tre) (RN-tre)
Gene: USP6NL

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.68	1.00	0.827

Property	Details
Experiments	30639242, 30194290, 34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	RabGAP-TBC~Ras
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 189 Hs			1 828
+	Hs
		349541 RASH_HUMAN (1-188): 6.53e-87: 255: 86.77		US6NL_HUMAN (1-828): 0: 882: 100.00
+	Hs
		348838 RASN_HUMAN (1-189): 2.37e-85: 251: 85.19		US6NL_HUMAN (1-828): 0: 882: 100.00
+	Hs
		1070334 RAB35_HUMAN (4-187): 1.09e-82: 244: 31.28		US6NL_HUMAN (1-828): 0: 882: 100.00
+	Hs
		234370 RB11A_HUMAN (4-184): 2.43e-72: 219: 33.88		EVI5_HUMAN (17-591): 7.71e-114: 367: 19.55
+	Hs
		349612 RASH_HUMAN (1-188): 6.53e-87: 255: 86.77		TB10A_HUMAN (27-503): 9.92e-102: 326: 24.07
+	Hs
		349367 RASH_HUMAN (1-188): 6.53e-87: 255: 86.77		TB10B_HUMAN (23-459): 7.98e-93: 311: 23.87
+	Hs
		1070219 RAB35_HUMAN (4-187): 1.09e-82: 244: 31.28		TB10B_HUMAN (23-459): 7.98e-93: 311: 23.87
+	Hs
		350509 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		TB10A_HUMAN (27-503): 9.92e-102: 326: 24.07
+	Hs
		1070473 RAB35_HUMAN (4-187): 1.09e-82: 244: 31.28		RBGP1_HUMAN (59-586): 1.36e-90: 310: 19.46
+	Hs
		350278 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		TBCD9_HUMAN (57-707): 2e-94: 323: 15.63
+	Hs
		895137 RAB2A_HUMAN (4-183): 1.46e-75: 227: 32.97		TBCD9_HUMAN (57-707): 2e-94: 323: 15.63
+	Hs
		350213 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		TB10B_HUMAN (23-459): 7.98e-93: 311: 23.87
+	Hs
		895106 RAB2A_HUMAN (4-183): 1.46e-75: 227: 32.97		TB10B_HUMAN (23-459): 7.98e-93: 311: 23.87
+	Hs
		914275 RB11A_HUMAN (4-184): 2.43e-72: 219: 33.88		EVI5L_HUMAN (70-591): 3.09e-94: 314: 21.29
+	Hs
		914482 RB11A_HUMAN (4-184): 2.43e-72: 219: 33.88		RBGP1_HUMAN (59-586): 1.36e-90: 310: 19.46
+	Hs
		914176 RB11A_HUMAN (4-184): 2.43e-72: 219: 33.88		TBCD1_HUMAN (2-455): 5.05e-88: 304: 20.93
+	Hs
		233036 RB11A_HUMAN (4-184): 2.43e-72: 219: 33.88		TBC12_HUMAN (77-325): 2.09e-22: 105: 27.51