HitPredict

Interactor 1: RASK (P01116)
GTPase KRas (EC 3.6.5.2) (K-Ras 2) (Ki-Ras) (c-K-ras) (c-Ki-ras) [Cleaved into: GTPase KRas, N-terminally processed]
Gene: KRAS

Interactor 2: SYTL4 (Q96C24)
Synaptotagmin-like protein 4 (Exophilin-2) (Granuphilin)
Gene: SYTL4

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	1.00	0.754

Property	Details
Experiments	30442766, 30194290
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	FYVE_2~Ras
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 189 Hs			1 671
+	Hs
		349554 RASH_HUMAN (1-188): 6.53e-87: 255: 86.77		SYTL4_HUMAN (1-671): 0: 587: 100.00
+	Hs
		348852 RASN_HUMAN (1-189): 2.37e-85: 251: 85.19		SYTL4_HUMAN (1-671): 0: 587: 100.00
+	Hs
		914274 RB11A_HUMAN (4-184): 2.43e-72: 219: 33.88		SYTL4_HUMAN (1-671): 0: 587: 100.00
+	Hs
		914240 RB11A_HUMAN (4-184): 2.43e-72: 219: 33.88		SYTL5_HUMAN (2-669): 9.15e-161: 481: 38.17
+	Hs
		1134943 RAB1B_HUMAN (4-187): 1.21e-73: 221: 32.47		SYT6_HUMAN (224-660): 2.2e-85: 279: 21.56
+	Hs
		896633 RAB14_HUMAN (4-184): 3.77e-72: 218: 29.51		SYT6_HUMAN (224-660): 2.2e-85: 279: 21.56
+	Hs
		897901 RAP1B_HUMAN (1-165): 1.02e-62: 193: 57.49		SYT6_HUMAN (224-660): 2.2e-85: 279: 21.56
+	Hs
		207682 RASH_HUMAN (1-188): 6.53e-87: 255: 86.77		SYT7_HUMAN (509-664): 8.34e-33: 132: 29.49
+	Hs
		207683 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		SYT7_HUMAN (509-664): 8.34e-33: 132: 29.49
+	Hs
		129082 RAB1A_HUMAN (4-187): 7.4e-74: 222: 34.36		SYT5_HUMAN (347-458): 3.13e-19: 92.2: 31.25