HitPredict

Interactor 1: RASK (P01116)
GTPase KRas (EC 3.6.5.2) (K-Ras 2) (Ki-Ras) (c-K-ras) (c-Ki-ras) [Cleaved into: GTPase KRas, N-terminally processed]
Gene: KRAS

Interactor 2: FMNL2 (Q96PY5)
Formin-like protein 2 (Formin homology 2 domain-containing protein 2)
Gene: FMNL2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Drf_FH3~Ras, Drf_GBD~Ras
Common GO terms	GO:0005829 - cytosol
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 189 Hs			1 1086
+	Hs
		349576 RASH_HUMAN (1-188): 6.53e-87: 255: 86.77		FMNL2_HUMAN (1-1086): 0: 1035: 100.00
+	Hs
		1070349 RAB35_HUMAN (4-187): 1.09e-82: 244: 31.28		FMNL2_HUMAN (1-1086): 0: 1035: 100.00
+	Hs
		895231 RAB2A_HUMAN (4-183): 1.46e-75: 227: 32.97		FMNL2_HUMAN (1-1086): 0: 1035: 100.00
+	Hs
		349679 RASH_HUMAN (1-188): 6.53e-87: 255: 86.77		DIAP3_HUMAN (177-1072): 0: 605: 21.41
+	Hs
		1070413 RAB35_HUMAN (4-187): 1.09e-82: 244: 31.28		DIAP3_HUMAN (177-1072): 0: 605: 21.41
+	Hs
		350593 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		DIAP3_HUMAN (177-1072): 0: 605: 21.41
+	Hs
		914389 RB11A_HUMAN (4-184): 2.43e-72: 219: 33.88		DIAP3_HUMAN (177-1072): 0: 605: 21.41
+	Hs
		349766 RASH_HUMAN (1-188): 6.53e-87: 255: 86.77		FHOD1_HUMAN (224-1079): 1.74e-151: 483: 15.51
+	Hs
		314855 RB11A_HUMAN (4-184): 2.43e-72: 219: 33.88		FMNL1_HUMAN (612-1083): 1.21e-130: 426: 56.99
+	Hs
		243098 RB11A_HUMAN (4-184): 2.43e-72: 219: 33.88		DIAP2_HUMAN (611-1073): 1.6e-119: 396: 20.84
+	Hs
		348969 RASN_HUMAN (1-189): 2.37e-85: 251: 85.19		FMN2_HUMAN (566-1036): 1.13e-87: 312: 20.40
+	Hs
		1070423 RAB35_HUMAN (4-187): 1.09e-82: 244: 31.28		FMN2_HUMAN (566-1036): 1.13e-87: 312: 20.40
+	Hs
		350619 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		FMN2_HUMAN (566-1036): 1.13e-87: 312: 20.40
+	Hs
		895300 RAB2A_HUMAN (4-183): 1.46e-75: 227: 32.97		FMN2_HUMAN (566-1036): 1.13e-87: 312: 20.40
+	Hs
		237598 RAB35_HUMAN (4-187): 1.09e-82: 244: 31.28		DIAP1_HUMAN (97-651): 1.74e-55: 212: 17.38
+	Hs
		237546 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		DIAP1_HUMAN (97-651): 1.74e-55: 212: 17.38
+	Hs
		1070213 RAB35_HUMAN (4-187): 1.09e-82: 244: 31.28		INF2_HUMAN (224-368): 3.51e-16: 86.3: 33.56
+	Hs
		350206 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		INF2_HUMAN (224-368): 3.51e-16: 86.3: 33.56
+	Hs
		914097 RB11A_HUMAN (4-184): 2.43e-72: 219: 33.88		INF2_HUMAN (224-368): 3.51e-16: 86.3: 33.56