HitPredict

Interactor 1: RASK (P01116)
GTPase KRas (EC 3.6.5.2) (K-Ras 2) (Ki-Ras) (c-K-ras) (c-Ki-ras) [Cleaved into: GTPase KRas, N-terminally processed]
Gene: KRAS

Interactor 2: TB10A (Q9BXI6)
TBC1 domain family member 10A (EBP50-PDX interactor of 64 kDa) (EPI64 protein) (Rab27A-GAP-alpha)
Gene: TBC1D10A

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	1.00	0.754

Property	Details
Experiments	30194290, 34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	RabGAP-TBC~Ras
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 189 Hs			1 508
+	Hs
		349612 RASH_HUMAN (1-188): 6.53e-87: 255: 86.77		TB10A_HUMAN (1-508): 6.34e-156: 455: 100.00
+	Hs
		349367 RASH_HUMAN (1-188): 6.53e-87: 255: 86.77		TB10B_HUMAN (5-465): 8.33e-128: 393: 59.44
+	Hs
		1070219 RAB35_HUMAN (4-187): 1.09e-82: 244: 31.28		TB10B_HUMAN (5-465): 8.33e-128: 393: 59.44
+	Hs
		350213 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		TB10B_HUMAN (5-465): 8.33e-128: 393: 59.44
+	Hs
		895106 RAB2A_HUMAN (4-183): 1.46e-75: 227: 32.97		TB10B_HUMAN (5-465): 8.33e-128: 393: 59.44
+	Hs
		349541 RASH_HUMAN (1-188): 6.53e-87: 255: 86.77		US6NL_HUMAN (24-507): 3.76e-108: 342: 24.25
+	Hs
		348838 RASN_HUMAN (1-189): 2.37e-85: 251: 85.19		US6NL_HUMAN (24-507): 3.76e-108: 342: 24.25
+	Hs
		1070334 RAB35_HUMAN (4-187): 1.09e-82: 244: 31.28		US6NL_HUMAN (24-507): 3.76e-108: 342: 24.25
+	Hs
		350417 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		US6NL_HUMAN (24-507): 3.76e-108: 342: 24.25
+	Hs
		1070473 RAB35_HUMAN (4-187): 1.09e-82: 244: 31.28		RBGP1_HUMAN (5-504): 9.58e-92: 303: 22.67
+	Hs
		914482 RB11A_HUMAN (4-184): 2.43e-72: 219: 33.88		RBGP1_HUMAN (5-504): 9.58e-92: 303: 22.67
+	Hs
		1070461 RAB35_HUMAN (4-187): 1.09e-82: 244: 31.28		TBD2B_HUMAN (11-380): 1.37e-81: 274: 24.39
+	Hs
		914275 RB11A_HUMAN (4-184): 2.43e-72: 219: 33.88		EVI5L_HUMAN (13-505): 1.31e-91: 298: 19.35
+	Hs
		350278 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		TBCD9_HUMAN (65-354): 4.84e-84: 284: 27.65
+	Hs
		895137 RAB2A_HUMAN (4-183): 1.46e-75: 227: 32.97		TBCD9_HUMAN (65-354): 4.84e-84: 284: 27.65
+	Hs
		914176 RB11A_HUMAN (4-184): 2.43e-72: 219: 33.88		TBCD1_HUMAN (7-477): 5.21e-84: 283: 21.37
+	Hs
		234370 RB11A_HUMAN (4-184): 2.43e-72: 219: 33.88		EVI5_HUMAN (79-503): 1.57e-83: 277: 21.35
+	Hs
		914465 RB11A_HUMAN (4-184): 2.43e-72: 219: 33.88		TBD2B_HUMAN (11-380): 1.37e-81: 274: 24.39
+	Hs
		321281 RB11A_HUMAN (4-184): 2.43e-72: 219: 33.88		TBCD8_HUMAN (100-312): 1.41e-29: 125: 35.35