HitPredict

Interactor 1: RASK (P01116)
GTPase KRas (EC 3.6.5.2) (K-Ras 2) (Ki-Ras) (c-K-ras) (c-Ki-ras) [Cleaved into: GTPase KRas, N-terminally processed]
Gene: KRAS

Interactor 2: DOCK9 (Q9BZ29)
Dedicator of cytokinesis protein 9 (Cdc42 guanine nucleotide exchange factor zizimin-1) (Zizimin-1)
Gene: DOCK9

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	1.00	0.754

Property	Details
Experiments	30639242, 34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	DHR-2_Lobe_B~Ras, DHR-2_Lobe_C~Ras, PH~Ras
Common GO terms	GO:0005829 - cytosol GO:0016020 - membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 189 Hs			1 2069
+	Hs
		349619 RASH_HUMAN (1-188): 6.53e-87: 255: 86.77		DOCK9_HUMAN (1-2069): 0: 2505: 100.00
+	Hs
		1070378 RAB35_HUMAN (4-187): 1.09e-82: 244: 31.28		DOCK9_HUMAN (1-2069): 0: 2505: 100.00
+	Hs
		350225 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		DOC11_HUMAN (11-2068): 0: 2189: 58.38
+	Hs
		350167 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		DOCK1_HUMAN (395-1220): 0: 616: 13.87
+	Hs
		349648 RASH_HUMAN (1-188): 6.53e-87: 255: 86.77		DOCK5_HUMAN (395-1224): 1.09e-163: 553: 13.46
+	Hs
		350557 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		DOCK5_HUMAN (395-1224): 1.09e-163: 553: 13.46
+	Hs
		349293 RASH_HUMAN (1-188): 6.53e-87: 255: 86.77		GAB1_HUMAN (171-470): 2.06e-66: 242: 17.39
+	Hs
		348648 RASN_HUMAN (1-189): 2.37e-85: 251: 85.19		GAB1_HUMAN (171-470): 2.06e-66: 242: 17.39
+	Hs
		1035374 RAB35_HUMAN (4-187): 1.09e-82: 244: 31.28		GAB1_HUMAN (171-470): 2.06e-66: 242: 17.39
+	Hs
		350144 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		GAB1_HUMAN (171-470): 2.06e-66: 242: 17.39
+	Hs
		348871 RASN_HUMAN (1-189): 2.37e-85: 251: 85.19		DOCK7_HUMAN (11-205): 1.33e-48: 194: 24.88
+	Hs
		1070346 RAB35_HUMAN (4-187): 1.09e-82: 244: 31.28		DOCK7_HUMAN (11-205): 1.33e-48: 194: 24.88
+	Hs
		349739 RASH_HUMAN (1-188): 6.53e-87: 255: 86.77		GAB2_HUMAN (170-500): 1.2e-43: 173: 18.38
+	Hs
		349503 RASH_HUMAN (1-188): 6.53e-87: 255: 86.77		DOCK8_HUMAN (7-167): 4.89e-42: 172: 21.23
+	Hs
		349013 RASN_HUMAN (1-189): 2.37e-85: 251: 85.19		GAB2_HUMAN (170-500): 1.2e-43: 173: 18.38
+	Hs
		348804 RASN_HUMAN (1-189): 2.37e-85: 251: 85.19		DOCK8_HUMAN (7-167): 4.89e-42: 172: 21.23
+	Hs
		350459 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		DOCK7_HUMAN (11-205): 1.33e-48: 194: 24.88
+	Hs
		350368 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		DOCK8_HUMAN (7-167): 4.89e-42: 172: 21.23
+	Hs
		348931 RASN_HUMAN (1-189): 2.37e-85: 251: 85.19		PKHA1_HUMAN (149-366): 8.42e-36: 143: 18.83
+	Hs
		1070403 RAB35_HUMAN (4-187): 1.09e-82: 244: 31.28		PKHA1_HUMAN (149-366): 8.42e-36: 143: 18.83