HitPredict

Interactor 1: RASK (P01116)
GTPase KRas (EC 3.6.5.2) (K-Ras 2) (Ki-Ras) (c-K-ras) (c-Ki-ras) [Cleaved into: GTPase KRas, N-terminally processed]
Gene: KRAS

Interactor 2: SPY4 (Q9C004)
Protein sprouty homolog 4 (Spry-4)
Gene: SPRY4

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.60	0.640

Property	Details
Experiments	30442766, 30194290, 34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005925 - focal adhesion
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 189 Hs			1 299
+	Hs
		349623 RASH_HUMAN (1-188): 6.53e-87: 255: 86.77		SPY4_HUMAN (1-299): 7.34e-127: 365: 100.00
+	Hs
		348907 RASN_HUMAN (1-189): 2.37e-85: 251: 85.19		SPY4_HUMAN (1-299): 7.34e-127: 365: 100.00
+	Hs
		1070382 RAB35_HUMAN (4-187): 1.09e-82: 244: 31.28		SPY4_HUMAN (1-299): 7.34e-127: 365: 100.00
+	Hs
		895255 RAB2A_HUMAN (4-183): 1.46e-75: 227: 32.97		SPY4_HUMAN (1-299): 7.34e-127: 365: 100.00
+	Hs
		914338 RB11A_HUMAN (4-184): 2.43e-72: 219: 33.88		SPY4_HUMAN (1-299): 7.34e-127: 365: 100.00
+	Hs
		208083 RASH_HUMAN (1-188): 6.53e-87: 255: 86.77		SPY2_HUMAN (27-291): 9.66e-99: 294: 39.86
+	Hs
		208084 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		SPY2_HUMAN (27-291): 9.66e-99: 294: 39.86
+	Hs
		350297 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		SPRE2_HUMAN (115-264): 1.21e-47: 166: 19.36
+	Hs
		914173 RB11A_HUMAN (4-184): 2.43e-72: 219: 33.88		SPRE1_HUMAN (97-259): 6.2e-51: 175: 21.30