HitPredict

Interactor 1: RASK (P01116)
GTPase KRas (EC 3.6.5.2) (K-Ras 2) (Ki-Ras) (c-K-ras) (c-Ki-ras) [Cleaved into: GTPase KRas, N-terminally processed]
Gene: KRAS

Interactor 2: TANC1 (Q9C0D5)
Protein TANC1 (Tetratricopeptide repeat, ankyrin repeat and coiled-coil domain-containing protein 1)
Gene: TANC1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	1.00	0.754

Property	Details
Experiments	30639242, 34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Ank~Ras, Ank_2~Ras, Ank_4~Ras
Common GO terms	GO:0008542 - visual learning
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 189 Hs			1 1861
+	Hs
		348910 RASN_HUMAN (1-189): 2.37e-85: 251: 85.19		TANC1_HUMAN (1-1861): 0: 1674: 100.00
+	Hs
		1070386 RAB35_HUMAN (4-187): 1.09e-82: 244: 31.28		TANC1_HUMAN (1-1861): 0: 1674: 100.00
+	Hs
		349001 RASN_HUMAN (1-189): 2.37e-85: 251: 85.19		ANR50_HUMAN (385-1762): 0: 692: 21.25
+	Hs
		350675 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		ANR50_HUMAN (385-1762): 0: 692: 21.25
+	Hs
		1021405 RAB35_HUMAN (4-187): 1.09e-82: 244: 31.28		ANK3_HUMAN (758-1857): 3.69e-163: 558: 13.95
+	Hs
		350123 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		ANK3_HUMAN (758-1857): 3.69e-163: 558: 13.95
+	Dm
		65552 RALA_DROME (4-182): 3.4e-60: 187: 52.22		A8JNM5_DROME (743-1857): 3.99e-171: 583: 15.51
+	Dm
		1248518 Q962I2_DROME (4-178): 1.03e-60: 189: 51.14		Q8SWY2_DROME (699-1478): 1.09e-140: 466: 18.01
+	Hs
		349253 RASH_HUMAN (1-188): 6.53e-87: 255: 86.77		ANK2_HUMAN (832-1445): 1.76e-99: 360: 19.88
+	Hs
		350083 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		ANK2_HUMAN (832-1445): 1.76e-99: 360: 19.88
+	Hs
		349000 RASN_HUMAN (1-189): 2.37e-85: 251: 85.19		KDIS_HUMAN (1153-1294): 5.61e-31: 136: 26.67
+	Hs
		1070450 RAB35_HUMAN (4-187): 1.09e-82: 244: 31.28		KDIS_HUMAN (1153-1294): 5.61e-31: 136: 26.67
+	Hs
		350674 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		KDIS_HUMAN (1153-1294): 5.61e-31: 136: 26.67
+	Hs
		895318 RAB2A_HUMAN (4-183): 1.46e-75: 227: 32.97		KDIS_HUMAN (1153-1294): 5.61e-31: 136: 26.67
+	Hs
		914450 RB11A_HUMAN (4-184): 2.43e-72: 219: 33.88		KDIS_HUMAN (1153-1294): 5.61e-31: 136: 26.67
+	Hs
		349212 RASH_HUMAN (1-188): 6.53e-87: 255: 86.77		DAPK1_HUMAN (1137-1270): 4.08e-10: 67.4: 32.09
+	Mm
		71299 RAB13_MOUSE (4-188): 2.76e-75: 226: 35.05		ANR44_MOUSE (595-897): 2.1e-17: 90.9: 8.63
+	Hs
		862018 RB11A_HUMAN (4-184): 2.43e-72: 219: 33.88		DAPK1_HUMAN (1137-1270): 4.08e-10: 67.4: 32.09