HitPredict

Interactor 1: RASK (P01116)
GTPase KRas (EC 3.6.5.2) (K-Ras 2) (Ki-Ras) (c-K-ras) (c-Ki-ras) [Cleaved into: GTPase KRas, N-terminally processed]
Gene: KRAS

Interactor 2: SEM6A (Q9H2E6)
Semaphorin-6A (Semaphorin VIA) (Sema VIA) (Semaphorin-6A-1) (SEMA6A-1)
Gene: SEMA6A

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0016020 - membrane
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 189 Hs			1 1030
+	Hs
		348915 RASN_HUMAN (1-189): 2.37e-85: 251: 85.19		SEM6A_HUMAN (1-1030): 0: 1031: 100.00
+	Hs
		350373 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		SEM6D_HUMAN (4-1030): 0: 908: 44.34
+	Hs
		349625 RASH_HUMAN (1-188): 6.53e-87: 255: 86.77		SEM4C_HUMAN (1-666): 0: 601: 25.98
+	Hs
		348909 RASN_HUMAN (1-189): 2.37e-85: 251: 85.19		SEM4C_HUMAN (1-666): 0: 601: 25.98
+	Hs
		1070385 RAB35_HUMAN (4-187): 1.09e-82: 244: 31.28		SEM4C_HUMAN (1-666): 0: 601: 25.98
+	Hs
		350524 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		SEM4C_HUMAN (1-666): 0: 601: 25.98
+	Hs
		914341 RB11A_HUMAN (4-184): 2.43e-72: 219: 33.88		SEM4C_HUMAN (1-666): 0: 601: 25.98
+	Hs
		348840 RASN_HUMAN (1-189): 2.37e-85: 251: 85.19		SEM4D_HUMAN (8-847): 0: 551: 22.39
+	Hs
		350423 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		SEM4D_HUMAN (8-847): 0: 551: 22.39
+	Hs
		195964 RASH_HUMAN (1-188): 6.53e-87: 255: 86.77		PLXB1_HUMAN (45-949): 1.68e-156: 512: 16.80
+	Mm
		914512 RB11A_MOUSE (4-184): 2.43e-72: 219: 33.88		SEM4A_MOUSE (25-660): 3.46e-162: 498: 26.15