HitPredict

Interactor 1: RASK (P01116)
GTPase KRas (EC 3.6.5.2) (K-Ras 2) (Ki-Ras) (c-K-ras) (c-Ki-ras) [Cleaved into: GTPase KRas, N-terminally processed]
Gene: KRAS

Interactor 2: PKHA2 (Q9HB19)
Pleckstrin homology domain-containing family A member 2 (PH domain-containing family A member 2) (Tandem PH domain-containing protein 2) (TAPP-2)
Gene: PLEKHA2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	19786618
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PH~Ras
Common GO terms	GO:0005737 - cytoplasm GO:0005886 - plasma membrane GO:0016020 - membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 189 Hs			1 425
+	Hs
		348931 RASN_HUMAN (1-189): 2.37e-85: 251: 85.19		PKHA1_HUMAN (1-425): 7.64e-108: 325: 44.21
+	Hs
		1070403 RAB35_HUMAN (4-187): 1.09e-82: 244: 31.28		PKHA1_HUMAN (1-425): 7.64e-108: 325: 44.21
+	Hs
		309422 RASH_HUMAN (1-188): 6.53e-87: 255: 86.77		MTMR5_HUMAN (3-298): 4.14e-49: 181: 17.56
+	Hs
		309421 RASN_HUMAN (1-189): 2.37e-85: 251: 85.19		MTMR5_HUMAN (3-298): 4.14e-49: 181: 17.56
+	Hs
		1070275 RAB35_HUMAN (4-187): 1.09e-82: 244: 31.28		MTMRD_HUMAN (4-298): 2.07e-49: 182: 17.70
+	Hs
		309483 RAB35_HUMAN (4-187): 1.09e-82: 244: 31.28		MTMR5_HUMAN (3-298): 4.14e-49: 181: 17.56
+	Hs
		309423 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		MTMR5_HUMAN (3-298): 4.14e-49: 181: 17.56
+	Hs
		299225 RASN_HUMAN (1-189): 2.37e-85: 251: 85.19		FARP2_HUMAN (78-329): 6.57e-40: 154: 17.83
+	Hs
		349655 RASH_HUMAN (1-188): 6.53e-87: 255: 86.77		PKHA5_HUMAN (118-392): 3.97e-37: 146: 15.05
+	Hs
		348930 RASN_HUMAN (1-189): 2.37e-85: 251: 85.19		PKHA5_HUMAN (118-392): 3.97e-37: 146: 15.05
+	Hs
		1070251 RAB35_HUMAN (4-187): 1.09e-82: 244: 31.28		PKHA7_HUMAN (118-420): 6.77e-39: 151: 16.81
+	Hs
		349026 RASN_HUMAN (1-189): 2.37e-85: 251: 85.19		FARP1_HUMAN (27-311): 1.73e-35: 141: 15.46
+	Hs
		1070402 RAB35_HUMAN (4-187): 1.09e-82: 244: 31.28		PKHA5_HUMAN (118-392): 3.97e-37: 146: 15.05
+	Hs
		1066121 RAB35_HUMAN (4-187): 1.09e-82: 244: 31.28		ACAP2_HUMAN (15-361): 3.99e-37: 145: 16.00
+	Hs
		1070476 RAB35_HUMAN (4-187): 1.09e-82: 244: 31.28		FARP1_HUMAN (27-311): 1.73e-35: 141: 15.46
+	Hs
		299226 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		FARP2_HUMAN (78-329): 6.57e-40: 154: 17.83
+	Hs
		350257 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		PKHA7_HUMAN (118-420): 6.77e-39: 151: 16.81
+	Hs
		350563 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		PKHA5_HUMAN (118-392): 3.97e-37: 146: 15.05
+	Hs
		349535 RASH_HUMAN (1-188): 6.53e-87: 255: 86.77		ARAP2_HUMAN (185-326): 3.94e-12: 70.4: 18.18
+	Hs
		350406 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		ARAP2_HUMAN (185-326): 3.94e-12: 70.4: 18.18