HitPredict

Interactor 1: RASK (P01116)
GTPase KRas (EC 3.6.5.2) (K-Ras 2) (Ki-Ras) (c-K-ras) (c-Ki-ras) [Cleaved into: GTPase KRas, N-terminally processed]
Gene: KRAS

Interactor 2: ANR50 (Q9ULJ7)
Ankyrin repeat domain-containing protein 50
Gene: ANKRD50

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.80	0.675

Property	Details
Experiments	30194290, 34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Ank~Ras, Ank_2~Ras, Ank_4~Ras
Common GO terms	-
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 189 Hs			1 1429
+	Hs
		349001 RASN_HUMAN (1-189): 2.37e-85: 251: 85.19		ANR50_HUMAN (1-1429): 0: 1249: 100.00
+	Hs
		349253 RASH_HUMAN (1-188): 6.53e-87: 255: 86.77		ANK2_HUMAN (703-1274): 1.38e-116: 408: 21.82
+	Hs
		350083 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		ANK2_HUMAN (703-1274): 1.38e-116: 408: 21.82
+	Mm
		71299 RAB13_MOUSE (4-188): 2.76e-75: 226: 35.05		ANR44_MOUSE (749-1247): 5.58e-101: 348: 26.30
+	Hs
		1021405 RAB35_HUMAN (4-187): 1.09e-82: 244: 31.28		ANK3_HUMAN (257-630): 1.75e-70: 264: 17.39
+	Dm
		65552 RALA_DROME (4-182): 3.4e-60: 187: 52.22		A8JNM5_DROME (278-764): 2.66e-84: 308: 18.89
+	Hs
		350123 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		ANK3_HUMAN (257-630): 1.75e-70: 264: 17.39
+	Hs
		348910 RASN_HUMAN (1-189): 2.37e-85: 251: 85.19		TANC1_HUMAN (311-679): 1.42e-57: 222: 21.37
+	Hs
		1070386 RAB35_HUMAN (4-187): 1.09e-82: 244: 31.28		TANC1_HUMAN (311-679): 1.42e-57: 222: 21.37
+	Hs
		350525 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		TANC1_HUMAN (311-679): 1.42e-57: 222: 21.37
+	Dm
		1248518 Q962I2_DROME (4-178): 1.03e-60: 189: 51.14		Q8SWY2_DROME (280-504): 2.67e-22: 106: 11.54