HitPredict

Interactor 1: RASK (P01116)
GTPase KRas (EC 3.6.5.2) (K-Ras 2) (Ki-Ras) (c-K-ras) (c-Ki-ras) [Cleaved into: GTPase KRas, N-terminally processed]
Gene: KRAS

Interactor 2: PLCL2 (Q9UPR0)
Inactive phospholipase C-like protein 2 (PLC-L(2)) (PLC-L2) (Phospholipase C-L2) (Phospholipase C-epsilon-2) (PLC-epsilon-2)
Gene: PLCL2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PH_12~Ras
Common GO terms	GO:0005737 - cytoplasm GO:0032228 - regulation of synaptic transmission, GABAergic
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 189 Hs			1 1127
+	Hs
		349735 RASH_HUMAN (1-188): 6.53e-87: 255: 86.77		PLCL2_HUMAN (1-1127): 0: 1518: 100.00
+	Hs
		349202 RASH_HUMAN (1-188): 6.53e-87: 255: 86.77		PLCD1_HUMAN (137-882): 0: 847: 36.16
+	Hs
		348580 RASN_HUMAN (1-189): 2.37e-85: 251: 85.19		PLCD1_HUMAN (137-882): 0: 847: 36.16
+	Hs
		349987 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		PLCD1_HUMAN (137-882): 0: 847: 36.16
+	Hs
		349665 RASH_HUMAN (1-188): 6.53e-87: 255: 86.77		PLCB1_HUMAN (125-925): 0: 802: 28.26
+	Hs
		348942 RASN_HUMAN (1-189): 2.37e-85: 251: 85.19		PLCB1_HUMAN (125-925): 0: 802: 28.26
+	Hs
		1070411 RAB35_HUMAN (4-187): 1.09e-82: 244: 31.28		PLCB1_HUMAN (125-925): 0: 802: 28.26
+	Hs
		350581 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		PLCB1_HUMAN (125-925): 0: 802: 28.26
+	Hs
		914080 RB11A_HUMAN (4-184): 2.43e-72: 219: 33.88		PLCB4_HUMAN (127-919): 0: 812: 28.64
+	Hs
		895288 RAB2A_HUMAN (4-183): 1.46e-75: 227: 32.97		PLCB1_HUMAN (125-925): 0: 802: 28.26
+	Hs
		253284 RASH_HUMAN (1-188): 6.53e-87: 255: 86.77		PLCH2_HUMAN (587-888): 3.89e-96: 337: 40.46
+	Hs
		348700 RASN_HUMAN (1-189): 2.37e-85: 251: 85.19		PLCH1_HUMAN (568-921): 1.47e-94: 334: 35.96
+	Hs
		349256 RASH_HUMAN (1-188): 6.53e-87: 255: 86.77		PLCB3_HUMAN (595-921): 2.29e-94: 330: 29.22
+	Hs
		1070221 RAB35_HUMAN (4-187): 1.09e-82: 244: 31.28		PLCH1_HUMAN (568-921): 1.47e-94: 334: 35.96
+	Hs
		350215 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		PLCH1_HUMAN (568-921): 1.47e-94: 334: 35.96
+	Hs
		895108 RAB2A_HUMAN (4-183): 1.46e-75: 227: 32.97		PLCH1_HUMAN (568-921): 1.47e-94: 334: 35.96
+	Hs
		350087 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		PLCB3_HUMAN (595-921): 2.29e-94: 330: 29.22
+	Hs
		349695 RASH_HUMAN (1-188): 6.53e-87: 255: 86.77		PLCE1_HUMAN (362-560): 6.85e-79: 287: 40.69
+	Hs
		580971 RB11A_HUMAN (4-184): 2.43e-72: 219: 33.88		PLCG1_HUMAN (604-907): 5.53e-91: 320: 36.48
+	Hs
		348976 RASN_HUMAN (1-189): 2.37e-85: 251: 85.19		PLCE1_HUMAN (362-560): 6.85e-79: 287: 40.69