HitPredict

Interactor 1: RASK (P01116)
GTPase KRas (EC 3.6.5.2) (K-Ras 2) (Ki-Ras) (c-K-ras) (c-Ki-ras) [Cleaved into: GTPase KRas, N-terminally processed]
Gene: KRAS

Interactor 2: SHOC2 (Q9UQ13)
Leucine-rich repeat protein SHOC-2 (Protein soc-2 homolog) (Protein sur-8 homolog)
Gene: SHOC2

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.60	0.600

Property	Details
Experiments	10783161, 34079125
Identification Methods	two hybrid, proximity labelling technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0007265 - Ras protein signal transduction
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 189 Hs			1 582
+	Hs
		349737 RASH_HUMAN (1-188): 6.53e-87: 255: 86.77		SHOC2_HUMAN (1-582): 9.48e-110: 341: 100.00
+	Hs
		349581 RASH_HUMAN (1-188): 6.53e-87: 255: 86.77		ERBIN_HUMAN (356-582): 9.64e-38: 151: 28.19
+	At
		955322 RAB1C_ARATH (4-182): 3.31e-72: 218: 30.94		BRL2_ARATH (57-419): 7.78e-50: 187: 18.88
+	Hs
		348879 RASN_HUMAN (1-189): 2.37e-85: 251: 85.19		ERBIN_HUMAN (356-582): 9.64e-38: 151: 28.19
+	Hs
		1070354 RAB35_HUMAN (4-187): 1.09e-82: 244: 31.28		ERBIN_HUMAN (356-582): 9.64e-38: 151: 28.19
+	Hs
		350468 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		ERBIN_HUMAN (356-582): 9.64e-38: 151: 28.19
+	Hs
		349319 RASH_HUMAN (1-188): 6.53e-87: 255: 86.77		SCRIB_HUMAN (87-435): 6.42e-29: 124: 30.05
+	Hs
		348663 RASN_HUMAN (1-189): 2.37e-85: 251: 85.19		SCRIB_HUMAN (87-435): 6.42e-29: 124: 30.05
+	Hs
		914297 RB11A_HUMAN (4-184): 2.43e-72: 219: 33.88		ERBIN_HUMAN (356-582): 9.64e-38: 151: 28.19
+	Hs
		1049954 RAB35_HUMAN (4-187): 1.09e-82: 244: 31.28		SCRIB_HUMAN (87-435): 6.42e-29: 124: 30.05
+	Hs
		350499 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		LRRC1_HUMAN (101-341): 9.34e-34: 136: 36.93
+	Ce
		612369 LET60_CAEEL (1-189): 1.63e-85: 251: 74.60		SHOC2_CAEEL (17-280): 1.32e-25: 112: 27.17
+	Hs
		350166 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		SCRIB_HUMAN (87-435): 6.42e-29: 124: 30.05
+	Hs
		232757 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		PHLP1_HUMAN (91-551): 2.22e-27: 120: 28.75
+	Hs
		914066 RB11A_HUMAN (4-184): 2.43e-72: 219: 33.88		SCRIB_HUMAN (87-435): 6.42e-29: 124: 30.05
+	Ce
		136853 RB11A_CAEEL (4-188): 1.02e-71: 217: 30.50		LAP1_CAEEL (104-272): 1.26e-16: 85.5: 33.73
+	Hs
		350129 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		FLII_HUMAN (91-300): 3.4e-11: 68.6: 27.62