HitPredict

Interactor 1: RASK (P01116)
GTPase KRas (EC 3.6.5.2) (K-Ras 2) (Ki-Ras) (c-K-ras) (c-Ki-ras) [Cleaved into: GTPase KRas, N-terminally processed]
Gene: KRAS

Interactor 2: PKHA6 (Q9Y2H5)
Pleckstrin homology domain-containing family A member 6 (PH domain-containing family A member 6) (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3)
Gene: PLEKHA6

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.553

Property	Details
Experiments	30639242
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PH~Ras
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 189 Hs			1 1048
+	Hs
		349655 RASH_HUMAN (1-188): 6.53e-87: 255: 86.77		PKHA5_HUMAN (1-1012): 2.52e-108: 365: 29.73
+	Hs
		348930 RASN_HUMAN (1-189): 2.37e-85: 251: 85.19		PKHA5_HUMAN (1-1012): 2.52e-108: 365: 29.73
+	Hs
		1070402 RAB35_HUMAN (4-187): 1.09e-82: 244: 31.28		PKHA5_HUMAN (1-1012): 2.52e-108: 365: 29.73
+	Hs
		1070251 RAB35_HUMAN (4-187): 1.09e-82: 244: 31.28		PKHA7_HUMAN (1-953): 1.72e-90: 315: 23.76
+	Hs
		349619 RASH_HUMAN (1-188): 6.53e-87: 255: 86.77		DOCK9_HUMAN (34-738): 2.37e-65: 244: 11.50
+	Hs
		1070378 RAB35_HUMAN (4-187): 1.09e-82: 244: 31.28		DOCK9_HUMAN (34-738): 2.37e-65: 244: 11.50
+	Hs
		350225 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		DOC11_HUMAN (47-721): 9.06e-68: 251: 9.76
+	Hs
		349384 RASH_HUMAN (1-188): 6.53e-87: 255: 86.77		RHG21_HUMAN (2-1037): 1.74e-52: 203: 11.31
+	Hs
		1070234 RAB35_HUMAN (4-187): 1.09e-82: 244: 31.28		RHG21_HUMAN (2-1037): 1.74e-52: 203: 11.31
+	Hs
		349120 RASH_HUMAN (1-188): 6.53e-87: 255: 86.77		RASA1_HUMAN (76-636): 1.95e-46: 183: 12.80
+	Hs
		348508 RASN_HUMAN (1-189): 2.37e-85: 251: 85.19		RASA1_HUMAN (76-636): 1.95e-46: 183: 12.80
+	Hs
		1066121 RAB35_HUMAN (4-187): 1.09e-82: 244: 31.28		ACAP2_HUMAN (32-407): 1.07e-46: 182: 14.56
+	Dm
		442996 RAS1_DROME (1-165): 9.63e-88: 257: 85.46		Q7KNQ9_DROME (23-287): 2.46e-41: 168: 20.22
+	Hs
		349874 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		RASA1_HUMAN (76-636): 1.95e-46: 183: 12.80
+	Hs
		349293 RASH_HUMAN (1-188): 6.53e-87: 255: 86.77		GAB1_HUMAN (57-571): 1.19e-38: 156: 13.15
+	Hs
		348648 RASN_HUMAN (1-189): 2.37e-85: 251: 85.19		GAB1_HUMAN (57-571): 1.19e-38: 156: 13.15
+	Hs
		1035374 RAB35_HUMAN (4-187): 1.09e-82: 244: 31.28		GAB1_HUMAN (57-571): 1.19e-38: 156: 13.15
+	Hs
		348931 RASN_HUMAN (1-189): 2.37e-85: 251: 85.19		PKHA1_HUMAN (47-251): 1.94e-34: 138: 26.24
+	Hs
		350144 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		GAB1_HUMAN (57-571): 1.19e-38: 156: 13.15
+	Hs
		1070403 RAB35_HUMAN (4-187): 1.09e-82: 244: 31.28		PKHA1_HUMAN (47-251): 1.94e-34: 138: 26.24