HitPredict

Interactor 1: RASK (P01116)
GTPase KRas (EC 3.6.5.2) (K-Ras 2) (Ki-Ras) (c-K-ras) (c-Ki-ras) [Cleaved into: GTPase KRas, N-terminally processed]
Gene: KRAS

Interactor 2: JAM1 (Q9Y624)
Junctional adhesion molecule A (JAM-A) (Junctional adhesion molecule 1) (JAM-1) (Platelet F11 receptor) (Platelet adhesion molecule 1) (PAM-1) (CD antigen CD321)
Gene: F11R

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.76	1.00	0.873

Property	Details
Experiments	30442766, 30639242, 30194290, 34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Ras~V-set
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 189 Hs			1 299
+	Hs
		349767 RASH_HUMAN (1-188): 6.53e-87: 255: 86.77		JAM1_HUMAN (1-299): 6.01e-72: 225: 100.00
+	Hs
		349034 RASN_HUMAN (1-189): 2.37e-85: 251: 85.19		JAM1_HUMAN (1-299): 6.01e-72: 225: 100.00
+	Hs
		1070483 RAB35_HUMAN (4-187): 1.09e-82: 244: 31.28		JAM1_HUMAN (1-299): 6.01e-72: 225: 100.00
+	Hs
		349610 RASH_HUMAN (1-188): 6.53e-87: 255: 86.77		JAM3_HUMAN (27-299): 5.24e-51: 172: 32.27
+	Hs
		348900 RASN_HUMAN (1-189): 2.37e-85: 251: 85.19		JAM3_HUMAN (27-299): 5.24e-51: 172: 32.27
+	Hs
		349237 RASH_HUMAN (1-188): 6.53e-87: 255: 86.77		CXAR_HUMAN (12-288): 1.06e-44: 157: 20.67
+	Hs
		348608 RASN_HUMAN (1-189): 2.37e-85: 251: 85.19		CXAR_HUMAN (12-288): 1.06e-44: 157: 20.67
+	Hs
		940426 RAB35_HUMAN (4-187): 1.09e-82: 244: 31.28		CXAR_HUMAN (12-288): 1.06e-44: 157: 20.67
+	Hs
		350058 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		CXAR_HUMAN (12-288): 1.06e-44: 157: 20.67
+	Hs
		349096 RASH_HUMAN (1-188): 6.53e-87: 255: 86.77		NCAM1_HUMAN (16-297): 4.21e-29: 118: 14.33
+	Hs
		348489 RASN_HUMAN (1-189): 2.37e-85: 251: 85.19		NCAM1_HUMAN (16-297): 4.21e-29: 118: 14.33
+	Hs
		530172 RAB35_HUMAN (4-187): 1.09e-82: 244: 31.28		NCAM1_HUMAN (16-297): 4.21e-29: 118: 14.33
+	Hs
		349841 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		NCAM1_HUMAN (16-297): 4.21e-29: 118: 14.33
+	Hs
		349775 RASH_HUMAN (1-188): 6.53e-87: 255: 86.77		ROBO1_HUMAN (1-169): 2.04e-17: 84.5: 12.14
+	Hs
		349043 RASN_HUMAN (1-189): 2.37e-85: 251: 85.19		ROBO1_HUMAN (1-169): 2.04e-17: 84.5: 12.14
+	Hs
		1070491 RAB35_HUMAN (4-187): 1.09e-82: 244: 31.28		ROBO1_HUMAN (1-169): 2.04e-17: 84.5: 12.14
+	Hs
		349395 RASH_HUMAN (1-188): 6.53e-87: 255: 86.77		CD276_HUMAN (33-227): 2.98e-12: 68.7: 17.97
+	Hs
		348723 RASN_HUMAN (1-189): 2.37e-85: 251: 85.19		CD276_HUMAN (33-227): 2.98e-12: 68.7: 17.97
+	Hs
		350246 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		CD276_HUMAN (33-227): 2.98e-12: 68.7: 17.97
+	Hs
		350405 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		TITIN_HUMAN (24-138): 4.1e-09: 59.9: 14.66