HitPredict

Interactor 1: RASK (P01116)
GTPase KRas (EC 3.6.5.2) (K-Ras 2) (Ki-Ras) (c-K-ras) (c-Ki-ras) [Cleaved into: GTPase KRas, N-terminally processed]
Gene: KRAS

Interactor 2: KC1G3 (Q9Y6M4)
Casein kinase I isoform gamma-3 (CKI-gamma 3) (EC 2.7.11.1)
Gene: CSNK1G3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	1.00	0.754

Property	Details
Experiments	30194290, 34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Pkinase~Ras
Common GO terms	GO:0005737 - cytoplasm GO:0005886 - plasma membrane
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 189 Hs			1 447
+	Hs
		349772 RASH_HUMAN (1-188): 6.53e-87: 255: 86.77		KC1G3_HUMAN (1-447): 2.1e-138: 406: 100.00
+	Hs
		349040 RASN_HUMAN (1-189): 2.37e-85: 251: 85.19		KC1G3_HUMAN (1-447): 2.1e-138: 406: 100.00
+	Hs
		1070488 RAB35_HUMAN (4-187): 1.09e-82: 244: 31.28		KC1G3_HUMAN (1-447): 2.1e-138: 406: 100.00
+	Hs
		895340 RAB2A_HUMAN (4-183): 1.46e-75: 227: 32.97		KC1G3_HUMAN (1-447): 2.1e-138: 406: 100.00
+	Hs
		914504 RB11A_HUMAN (4-184): 2.43e-72: 219: 33.88		KC1G3_HUMAN (1-447): 2.1e-138: 406: 100.00
+	Hs
		348610 RASN_HUMAN (1-189): 2.37e-85: 251: 85.19		KC1G2_HUMAN (5-447): 1.96e-125: 371: 75.23
+	Hs
		348536 RASN_HUMAN (1-189): 2.37e-85: 251: 85.19		AKT1_HUMAN (4-386): 2.58e-122: 366: 19.74
+	Hs
		682177 RAB35_HUMAN (4-187): 1.09e-82: 244: 31.28		AKT2_HUMAN (1-386): 6.22e-125: 373: 18.37
+	Hs
		822235 RAB1A_HUMAN (4-187): 7.4e-74: 222: 34.36		KC1D_HUMAN (36-435): 1.44e-134: 395: 46.29
+	Mm
		554949 Q9R0B8_MOUSE (38-188): 4.5e-86: 251: 82.90		KPCE_MOUSE (7-386): 5.85e-119: 365: 15.80
+	Hs
		349969 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		KC1A_HUMAN (28-364): 3.67e-130: 381: 50.59
+	Hs
		349916 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		AKT2_HUMAN (1-386): 6.22e-125: 373: 18.37
+	Hs
		350062 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		KC1G2_HUMAN (5-447): 1.96e-125: 371: 75.23
+	Hs
		682159 RAB2A_HUMAN (4-183): 1.46e-75: 227: 32.97		AKT2_HUMAN (1-386): 6.22e-125: 373: 18.37