Interactor 1: LDLR (P01130)
Low-density lipoprotein receptor (LDL receptor)
Gene: LDLR

Interactor 2: LDLR (P01130)
Low-density lipoprotein receptor (LDL receptor)
Gene: LDLR

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.41 1.00 0.647

The method score is based on:

Property Details
Experiments 26526611
Identification Methods surface plasmon resonance
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains EGF_CA~EGF_CA, EGF_CA~FXa_inhibition, EGF_CA~Ldl_recept_b, FXa_inhibition~FXa_inhibition, FXa_inhibition~Ldl_recept_a, FXa_inhibition~Ldl_recept_b, Ldl_recept_a~Ldl_recept_a, Ldl_recept_a~Ldl_recept_b, Ldl_recept_b~Ldl_recept_b
Common GO terms GO:0001540 - amyloid-beta binding
GO:0001618 - virus receptor activity
GO:0001920 - negative regulation of receptor recycling
GO:0002020 - protease binding
GO:0005041 - low-density lipoprotein particle receptor activity
and 60 others

more...

Homologous interactions 9

Homologous interactions

Color coding for hit scores

1 860
Hs

1 860
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024