Interactor 1: LDLR (P01130)
Low-density lipoprotein receptor (LDL receptor)
Gene: LDLR

Interactor 2: ARH (Q5SW96)
Low density lipoprotein receptor adapter protein 1 (Autosomal recessive hypercholesterolemia protein)
Gene: LDLRAP1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.41 0.60 0.501

The method score is based on:

Property Details
Experiments 12221107
Identification Methods pull down
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0001540 - amyloid-beta binding
GO:0005769 - early endosome
GO:0005886 - plasma membrane
GO:0006898 - receptor-mediated endocytosis
GO:0008203 - cholesterol metabolic process
and 5 others

more...

Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 860
Hs

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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024