HitPredict

Interactor 1: LDLR (P01130)
Low-density lipoprotein receptor (LDL receptor)
Gene: LDLR

Interactor 2: ZN408 (Q9H9D4)
Zinc finger protein 408 (PR domain zinc finger protein 17)
Gene: ZNF408

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.50	0.574

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 860 Hs			1 720
+	Hs
		254291 LRP4_HUMAN (664-846): 1.85e-17: 89.9: 14.75		ZN408_HUMAN (11-720): 0: 593: 100.00
+	Hs
		957528 VLDLR_HUMAN (187-454): 1.14e-15: 83.7: 21.56		ZN408_HUMAN (11-720): 0: 593: 100.00
+	Hs
		957644 LRP2_HUMAN (677-844): 3.13e-11: 69.9: 15.48		ZN408_HUMAN (11-720): 0: 593: 100.00
+	Hs
		1269022 SORL_HUMAN (17-104): 1.75e-09: 63.9: 43.33		ZN408_HUMAN (11-720): 0: 593: 100.00
+	Hs
		1334218 LRP1B_HUMAN (21-229): 6.4e-09: 62.2: 16.82		ZN408_HUMAN (11-720): 0: 593: 100.00
+	Hs
		254289 LRP4_HUMAN (664-846): 1.85e-17: 89.9: 14.75		ZN778_HUMAN (186-719): 6.11e-167: 499: 24.44
+	Hs
		1060253 SORL_HUMAN (17-104): 1.75e-09: 63.9: 43.33		ZN169_HUMAN (353-580): 5.46e-40: 157: 34.24
+	Hs
		1060268 LRP1B_HUMAN (21-229): 6.4e-09: 62.2: 16.82		ZN169_HUMAN (353-580): 5.46e-40: 157: 34.24
+	Hs
		254278 LRP4_HUMAN (664-846): 1.85e-17: 89.9: 14.75		ZN383_HUMAN (546-664): 9.95e-31: 128: 21.01
+	Hs
		270315 LRP6_HUMAN (194-374): 7.63e-12: 71.8: 26.60		ZN383_HUMAN (546-664): 9.95e-31: 128: 21.01
+	Hs
		258331 LRP5_HUMAN (195-364): 1.29e-10: 67.5: 26.14		ZN383_HUMAN (546-664): 9.95e-31: 128: 21.01