Interactor 1: EGF (P01133)
Pro-epidermal growth factor (EGF) [Cleaved into: Epidermal growth factor (Urogastrone)]
Gene: EGF
Interactor 2: EGF (P01133)
Pro-epidermal growth factor (EGF) [Cleaved into: Epidermal growth factor (Urogastrone)]
Gene: EGF
Species: Homo sapiens
Source: biogrid
Category: Small-scale
Confidence: High
Method score | Annotation score | Interaction score |
---|---|---|
0.33 | 1.00 | 0.575 |
The method score is based on:
Property | Details |
---|---|
Experiments | 11438527 |
Identification Methods | x-ray crystallography |
Interaction Type | association |
The annotation score is based on:
Property | Details |
---|---|
Interacting Pfam domains | EGF~EGF, EGF~EGF_CA, EGF~FXa_inhibition, EGF_CA~EGF_CA, EGF_CA~FXa_inhibition, EGF_CA~Ldl_recept_b, FXa_inhibition~FXa_inhibition, FXa_inhibition~Ldl_recept_b, Ldl_recept_b~Ldl_recept_b |
Common GO terms | GO:0001525 - angiogenesis GO:0001938 - positive regulation of endothelial cell proliferation GO:0002092 - positive regulation of receptor internalization GO:0005085 - guanyl-nucleotide exchange factor activity GO:0005154 - epidermal growth factor receptor binding and 45 others more... |
Homologous interactions | 14 |
Homologous interactions
Color coding for hit scores
Service provided by Combinatics, Japan
Last updated: 15 Jul 2024