Interactor 1: EGF (P01133)
Pro-epidermal growth factor (EGF) [Cleaved into: Epidermal growth factor (Urogastrone)]
Gene: EGF

Interactor 2: EGF (P01133)
Pro-epidermal growth factor (EGF) [Cleaved into: Epidermal growth factor (Urogastrone)]
Gene: EGF

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.33 1.00 0.575

The method score is based on:

Property Details
Experiments 11438527
Identification Methods x-ray crystallography
Interaction Type association

The annotation score is based on:

Property Details
Interacting Pfam domains EGF~EGF, EGF~EGF_CA, EGF~FXa_inhibition, EGF_CA~EGF_CA, EGF_CA~FXa_inhibition, EGF_CA~Ldl_recept_b, FXa_inhibition~FXa_inhibition, FXa_inhibition~Ldl_recept_b, Ldl_recept_b~Ldl_recept_b
Common GO terms GO:0001525 - angiogenesis
GO:0001938 - positive regulation of endothelial cell proliferation
GO:0002092 - positive regulation of receptor internalization
GO:0005085 - guanyl-nucleotide exchange factor activity
GO:0005154 - epidermal growth factor receptor binding
and 45 others

more...

Homologous interactions 14

Homologous interactions

Color coding for hit scores

1 1207
Hs

1 1207
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Last updated: 15 Jul 2024