Interactor 1: TGFB1 (P01137)
Transforming growth factor beta-1 proprotein [Cleaved into: Latency-associated peptide (LAP); Transforming growth factor beta-1 (TGF-beta-1)]
Gene: TGFB1

Interactor 2: TGFB1 (P01137)
Transforming growth factor beta-1 proprotein [Cleaved into: Latency-associated peptide (LAP); Transforming growth factor beta-1 (TGF-beta-1)]
Gene: TGFB1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.44 1.00 0.666

The method score is based on:

Property Details
Experiments 21677751
Identification Methods molecular sieving, transmission electron microscopy
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains TGF_beta~TGF_beta, TGF_beta~TGFb_propeptide, TGFb_propeptide~TGFb_propeptide
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000902 - cell morphogenesis
GO:0001570 - vasculogenesis
GO:0001657 - ureteric bud development
GO:0001837 - epithelial to mesenchymal transition
and 193 others

more...

Homologous interactions 15

Homologous interactions

Color coding for hit scores

1 390
Hs

1 390
+ Mm
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+ Hs
+ Hs
+ Hs
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+ Dm
+ Dm
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+ Mm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024