HitPredict

Interactor 1: TGFB1 (P01137)
Transforming growth factor beta-1 proprotein [Cleaved into: Latency-associated peptide (LAP); Transforming growth factor beta-1 (TGF-beta-1)]
Gene: TGFB1

Interactor 2: EGLN (P17813)
Endoglin (CD antigen CD105)
Gene: ENG

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.69 0.60 0.646

The method score is based on:

Property Details
Experiments 1326540, 8655583, 20856203
Identification Methods affinity chromatography technology, competition binding, cross-linking study
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0001570 - vasculogenesis
GO:0001837 - epithelial to mesenchymal transition
GO:0005114 - type II transforming growth factor beta receptor binding
GO:0005615 - extracellular space
and 14 others

more...
Homologous interactions 8

Homologous interactions

Color coding for hit scores

1 390
Hs

1 658
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024