Interactor 1: GLHA (P01215)
Glycoprotein hormones alpha chain (Anterior pituitary glycoprotein hormones common subunit alpha) (Choriogonadotropin alpha chain) (Chorionic gonadotrophin subunit alpha) (CG-alpha) (Follicle-stimulating hormone alpha chain) (FSH-alpha) (Follitropin alpha chain) (Luteinizing hormone alpha chain) (LSH-alpha) (Lutropin alpha chain) (Thyroid-stimulating hormone alpha chain) (TSH-alpha) (Thyrotropin alpha chain)
Gene: CGA

Interactor 2: CGB3 (P0DN86)
Choriogonadotropin subunit beta 3 (Choriogonadotropin subunit beta) (CG-beta) (Chorionic gonadotropin chain beta)
Gene: CGB3

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.57 1.00 0.757

The method score is based on:

Property Details
Experiments 7922031, unassigned1913
Identification Methods x-ray crystallography, split luciferase complementation
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Cys_knot~Hormone_6
Common GO terms GO:0005179 - hormone activity
GO:0005576 - extracellular region
GO:0005615 - extracellular space
GO:0007186 - G protein-coupled receptor signaling pathway
GO:0009755 - hormone-mediated signaling pathway
and 1 others

more...

Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 116
Hs

1 165
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024