Interactor 1: GLUC (P01275)
Pro-glucagon [Cleaved into: Glicentin; Glicentin-related polypeptide (GRPP); Oxyntomodulin (OXM) (OXY); Glucagon; Glucagon-like peptide 1 (GLP-1) (Incretin hormone); Glucagon-like peptide 1(7-37) (GLP-1(7-37)); Glucagon-like peptide 1(7-36) (GLP-1(7-36)); Glucagon-like peptide 2 (GLP-2)]
Gene: GCG

Interactor 2: INS (P01308)
Insulin [Cleaved into: Insulin B chain; Insulin A chain]
Gene: INS

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.38 0.55 0.458

The method score is based on:

Property Details
Experiments 32457219
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005179 - hormone activity
GO:0005576 - extracellular region
GO:0005615 - extracellular space
GO:0005788 - endoplasmic reticulum lumen
GO:0007186 - G protein-coupled receptor signaling pathway
and 2 others

more...

Homologous interactions 0

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Last updated: 15 Jul 2024